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Immunosuppressive FK506 treatment leads to more frequent EBV-associated lymphoproliferative disease in humanized mice
Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication after organ transplantation frequently associated with the Epstein-Barr virus (EBV). Immunosuppressive treatment is thought to allow the expansion of EBV-infected B cells, which often express all eight oncogenic...
Autores principales: | Caduff, Nicole, McHugh, Donal, Murer, Anita, Rämer, Patrick, Raykova, Ana, Landtwing, Vanessa, Rieble, Lisa, Keller, Christian W., Prummer, Michael, Hoffmann, Laurent, Lam, Janice K. P., Chiang, Alan K. S., Raulf, Friedrich, Azzi, Tarik, Berger, Christoph, Rubic-Schneider, Tina, Traggiai, Elisabetta, Lünemann, Jan D., Kammüller, Michael, Münz, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162544/ https://www.ncbi.nlm.nih.gov/pubmed/32251475 http://dx.doi.org/10.1371/journal.ppat.1008477 |
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