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Pericardial Effusion as an Initial Presentation of Panhypopituitarism

Pericardial effusion has a broad spectrum of clinical presentation, ranging from an incidental finding on imaging to a potentially fatal emergency such as pericardial tamponade, the most severe presentation. The authors present a case of a middle-aged male hospitalized due to shortness of breath. In...

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Detalles Bibliográficos
Autores principales: Alves, Rosa, Alegria, Sofia, Luiz, Henrique Vara, Judas, Tiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SMC Media Srl 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162561/
https://www.ncbi.nlm.nih.gov/pubmed/32309255
http://dx.doi.org/10.12890/2020_001478
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author Alves, Rosa
Alegria, Sofia
Luiz, Henrique Vara
Judas, Tiago
author_facet Alves, Rosa
Alegria, Sofia
Luiz, Henrique Vara
Judas, Tiago
author_sort Alves, Rosa
collection PubMed
description Pericardial effusion has a broad spectrum of clinical presentation, ranging from an incidental finding on imaging to a potentially fatal emergency such as pericardial tamponade, the most severe presentation. The authors present a case of a middle-aged male hospitalized due to shortness of breath. Initial work-up was positive for massive pericardial effusion with haemodynamic compromise. Additional study revealed panhypopituitarism. The acromegalic phenotype was suggestive of acromegaly secondary to pituitary adenoma, which had probably evolved to apoplexy. Hormone replacement was started with clinical improvement. At the 3-year follow-up, there was no evidence of recurrence of pericardial effusion. Panhypopituitarism is a relatively rare entity, but can lead to life-threatening complications such as adrenal crisis, coma and myxoedema-associated cardiac failure. Pericardial effusion is an extremely rare manifestation of secondary hypothyroidism. LEARNING POINTS: To recognize the clinical presentation of cardiac tamponade. To recognize atypical causes of pericardial effusion, such as severe panhypopituitarism. Hormonal replacement is efficient in treating panhypopituitarism.
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spelling pubmed-71625612020-04-17 Pericardial Effusion as an Initial Presentation of Panhypopituitarism Alves, Rosa Alegria, Sofia Luiz, Henrique Vara Judas, Tiago Eur J Case Rep Intern Med Articles Pericardial effusion has a broad spectrum of clinical presentation, ranging from an incidental finding on imaging to a potentially fatal emergency such as pericardial tamponade, the most severe presentation. The authors present a case of a middle-aged male hospitalized due to shortness of breath. Initial work-up was positive for massive pericardial effusion with haemodynamic compromise. Additional study revealed panhypopituitarism. The acromegalic phenotype was suggestive of acromegaly secondary to pituitary adenoma, which had probably evolved to apoplexy. Hormone replacement was started with clinical improvement. At the 3-year follow-up, there was no evidence of recurrence of pericardial effusion. Panhypopituitarism is a relatively rare entity, but can lead to life-threatening complications such as adrenal crisis, coma and myxoedema-associated cardiac failure. Pericardial effusion is an extremely rare manifestation of secondary hypothyroidism. LEARNING POINTS: To recognize the clinical presentation of cardiac tamponade. To recognize atypical causes of pericardial effusion, such as severe panhypopituitarism. Hormonal replacement is efficient in treating panhypopituitarism. SMC Media Srl 2020-02-24 /pmc/articles/PMC7162561/ /pubmed/32309255 http://dx.doi.org/10.12890/2020_001478 Text en © EFIM 2020 This article is licensed under a Commons Attribution Non-Commercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle Articles
Alves, Rosa
Alegria, Sofia
Luiz, Henrique Vara
Judas, Tiago
Pericardial Effusion as an Initial Presentation of Panhypopituitarism
title Pericardial Effusion as an Initial Presentation of Panhypopituitarism
title_full Pericardial Effusion as an Initial Presentation of Panhypopituitarism
title_fullStr Pericardial Effusion as an Initial Presentation of Panhypopituitarism
title_full_unstemmed Pericardial Effusion as an Initial Presentation of Panhypopituitarism
title_short Pericardial Effusion as an Initial Presentation of Panhypopituitarism
title_sort pericardial effusion as an initial presentation of panhypopituitarism
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162561/
https://www.ncbi.nlm.nih.gov/pubmed/32309255
http://dx.doi.org/10.12890/2020_001478
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