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Adding MASP1 to the lectin pathway—Leprosy association puzzle: Hints from gene polymorphisms and protein levels

BACKGROUND: Deposition of complement factors on Mycobacterium leprae may enhance phagocytosis. Such deposition may occur through the lectin pathway of complement. Three proteins of the lectin pathway are produced from the gene MASP1: Mannan-binding lectin-associated serine protease 1 (MASP-1) and MA...

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Detalles Bibliográficos
Autores principales: Weinschutz Mendes, Hellen, Boldt, Angelica Beate Winter, von Rosen Seeling Stahlke, Ewalda, Jensenius, Jens Christian, Thiel, Steffen, Messias-Reason, Iara J. Taborda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162614/
https://www.ncbi.nlm.nih.gov/pubmed/32240160
http://dx.doi.org/10.1371/journal.pntd.0007534