Cargando…

Features of anosmia in COVID-19

BACKGROUND: Medical publications about anosmia with COVID-19 are scarce. We aimed to describe the prevalence and features of anosmia in COVID-19 patients. METHODS: We retrospectively included COVID-19 patients with anosmia between March 1st and March 17th, 2020. We used SARS-CoV-2 real time PCR in r...

Descripción completa

Detalles Bibliográficos
Autores principales: Klopfenstein, T., Kadiane-Oussou, N.J., Toko, L., Royer, P.-Y., Lepiller, Q., Gendrin, V., Zayet, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162775/
https://www.ncbi.nlm.nih.gov/pubmed/32305563
http://dx.doi.org/10.1016/j.medmal.2020.04.006
_version_ 1783523089444765696
author Klopfenstein, T.
Kadiane-Oussou, N.J.
Toko, L.
Royer, P.-Y.
Lepiller, Q.
Gendrin, V.
Zayet, S.
author_facet Klopfenstein, T.
Kadiane-Oussou, N.J.
Toko, L.
Royer, P.-Y.
Lepiller, Q.
Gendrin, V.
Zayet, S.
author_sort Klopfenstein, T.
collection PubMed
description BACKGROUND: Medical publications about anosmia with COVID-19 are scarce. We aimed to describe the prevalence and features of anosmia in COVID-19 patients. METHODS: We retrospectively included COVID-19 patients with anosmia between March 1st and March 17th, 2020. We used SARS-CoV-2 real time PCR in respiratory samples to confirm the cases. RESULTS: Fifty-four of 114 patients (47%) with confirmed COVID-19 reported anosmia. Mean age of the 54 patients was 47 (± 16) years; 67% were females and 37% were hospitalised. The median Charlson comorbidity index was 0.70 (± 1.6 [0–7]). Forty-six patients (85%) had dysgeusia and 28% presented with pneumonia. Anosmia began 4.4 (± 1.9 [1–8]) days after infection onset. The mean duration of anosmia was 8.9 (± 6.3 [1–21]) days and 98% of patients recovered within 28 days. CONCLUSIONS: Anosmia was present in half of our European COVID-19 patients and was often associated with dysgeusia.
format Online
Article
Text
id pubmed-7162775
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier Masson SAS.
record_format MEDLINE/PubMed
spelling pubmed-71627752020-04-17 Features of anosmia in COVID-19 Klopfenstein, T. Kadiane-Oussou, N.J. Toko, L. Royer, P.-Y. Lepiller, Q. Gendrin, V. Zayet, S. Med Mal Infect Short Communication BACKGROUND: Medical publications about anosmia with COVID-19 are scarce. We aimed to describe the prevalence and features of anosmia in COVID-19 patients. METHODS: We retrospectively included COVID-19 patients with anosmia between March 1st and March 17th, 2020. We used SARS-CoV-2 real time PCR in respiratory samples to confirm the cases. RESULTS: Fifty-four of 114 patients (47%) with confirmed COVID-19 reported anosmia. Mean age of the 54 patients was 47 (± 16) years; 67% were females and 37% were hospitalised. The median Charlson comorbidity index was 0.70 (± 1.6 [0–7]). Forty-six patients (85%) had dysgeusia and 28% presented with pneumonia. Anosmia began 4.4 (± 1.9 [1–8]) days after infection onset. The mean duration of anosmia was 8.9 (± 6.3 [1–21]) days and 98% of patients recovered within 28 days. CONCLUSIONS: Anosmia was present in half of our European COVID-19 patients and was often associated with dysgeusia. Elsevier Masson SAS. 2020-08 2020-04-17 /pmc/articles/PMC7162775/ /pubmed/32305563 http://dx.doi.org/10.1016/j.medmal.2020.04.006 Text en © 2020 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Klopfenstein, T.
Kadiane-Oussou, N.J.
Toko, L.
Royer, P.-Y.
Lepiller, Q.
Gendrin, V.
Zayet, S.
Features of anosmia in COVID-19
title Features of anosmia in COVID-19
title_full Features of anosmia in COVID-19
title_fullStr Features of anosmia in COVID-19
title_full_unstemmed Features of anosmia in COVID-19
title_short Features of anosmia in COVID-19
title_sort features of anosmia in covid-19
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162775/
https://www.ncbi.nlm.nih.gov/pubmed/32305563
http://dx.doi.org/10.1016/j.medmal.2020.04.006
work_keys_str_mv AT klopfensteint featuresofanosmiaincovid19
AT kadianeoussounj featuresofanosmiaincovid19
AT tokol featuresofanosmiaincovid19
AT royerpy featuresofanosmiaincovid19
AT lepillerq featuresofanosmiaincovid19
AT gendrinv featuresofanosmiaincovid19
AT zayets featuresofanosmiaincovid19