Pathological manifestation of the induced pluripotent stem cell‐derived cortical neurons from an early‐onset Alzheimer's disease patient carrying a presenilin‐1 mutation (S170F)

OBJECTIVES: Alzheimer's disease (AD) is the most common neurodegenerative disease which is characterized by the formation of amyloid beta (Aβ) plaques and neurofibrillary tangles. These abnormal proteins induce disturbance in mitochondrial dynamics and defect in autophagy system. Since presenil...

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Detalles Bibliográficos
Autores principales: Li, Ling, Kim, Hee Jin, Roh, Jee Hoon, Kim, Minchul, Koh, Wonyoung, Kim, Younghoon, Heo, Hyohoon, Chung, Jaehoon, Nakanishi, Mahito, Yoon, Taeyoung, Hong, Chang Pyo, Seo, Sang Won, Na, Duk L., Song, Jihwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162796/
https://www.ncbi.nlm.nih.gov/pubmed/32216003
http://dx.doi.org/10.1111/cpr.12798

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