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Development of a tunable method to generate various three-dimensional microstructures by replenishing macromolecules such as extracellular matrix components and polysaccharides
Multicellular spheroids (spheroids) are expected to be a promising approach to mimic in vivo organ functions and cell microenvironments. However, conventional spheroids do not fully consider the existence of extracellular matrices (ECMs). In this study, we developed a tunable method for replenishing...
Autores principales: | Tao, Fumiya, Sayo, Kanae, Sugimoto, Kazuyuki, Aoki, Shigehisa, Kojima, Nobuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162899/ https://www.ncbi.nlm.nih.gov/pubmed/32300241 http://dx.doi.org/10.1038/s41598-020-63621-4 |
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