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Longterm outcome of anal fistula – A retrospective study

This retrospective observational study analyses the outcomes of patients undergoing surgery for anal fistula at a single centre in order to assess recurrence and re-operation rates after different surgical techniques. During January 2005 and May 2013, all patients with anal fistula were included. Ba...

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Autores principales: Andreou, Christos, Zeindler, Jasmin, Oertli, Daniel, Misteli, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162908/
https://www.ncbi.nlm.nih.gov/pubmed/32300218
http://dx.doi.org/10.1038/s41598-020-63541-3
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author Andreou, Christos
Zeindler, Jasmin
Oertli, Daniel
Misteli, Heidi
author_facet Andreou, Christos
Zeindler, Jasmin
Oertli, Daniel
Misteli, Heidi
author_sort Andreou, Christos
collection PubMed
description This retrospective observational study analyses the outcomes of patients undergoing surgery for anal fistula at a single centre in order to assess recurrence and re-operation rates after different surgical techniques. During January 2005 and May 2013, all patients with anal fistula were included. Baseline characteristics, details of presentation, fistula anatomy, type of surgery, post-surgical outcomes and follow-up data were collected. The primary endpoints were long-term closure rate and recurrence rate after 2 years. Secondary endpoints were persistent pain, postoperative complications and continence status. A total of 65 patients were included. From a total amount of 93 operations, 65 were fistulotomies, 13 mucosal advancement flaps, 7 anal fistula plugs and 8 cutting-setons. The mean follow up was 80 months. Healing was achieved in 85%. The highest recurrence rate was seen in anal fistula plug with 42%. On the other hand, no recurrence was observed in the cutting-seton procedures. For all included operation no persistent postoperative pain nor incontinence was observed. In conclusion, despite all existing anal fistula operations up to date, the optimal technique with low recurrence rate and assured safety for the anal sphincter is still lacking. Nonetheless, according to our promising results for the cutting-seton technique, this technique, otherwise considered obsolete, should be further evaluated in a prospective study.
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spelling pubmed-71629082020-04-22 Longterm outcome of anal fistula – A retrospective study Andreou, Christos Zeindler, Jasmin Oertli, Daniel Misteli, Heidi Sci Rep Article This retrospective observational study analyses the outcomes of patients undergoing surgery for anal fistula at a single centre in order to assess recurrence and re-operation rates after different surgical techniques. During January 2005 and May 2013, all patients with anal fistula were included. Baseline characteristics, details of presentation, fistula anatomy, type of surgery, post-surgical outcomes and follow-up data were collected. The primary endpoints were long-term closure rate and recurrence rate after 2 years. Secondary endpoints were persistent pain, postoperative complications and continence status. A total of 65 patients were included. From a total amount of 93 operations, 65 were fistulotomies, 13 mucosal advancement flaps, 7 anal fistula plugs and 8 cutting-setons. The mean follow up was 80 months. Healing was achieved in 85%. The highest recurrence rate was seen in anal fistula plug with 42%. On the other hand, no recurrence was observed in the cutting-seton procedures. For all included operation no persistent postoperative pain nor incontinence was observed. In conclusion, despite all existing anal fistula operations up to date, the optimal technique with low recurrence rate and assured safety for the anal sphincter is still lacking. Nonetheless, according to our promising results for the cutting-seton technique, this technique, otherwise considered obsolete, should be further evaluated in a prospective study. Nature Publishing Group UK 2020-04-16 /pmc/articles/PMC7162908/ /pubmed/32300218 http://dx.doi.org/10.1038/s41598-020-63541-3 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Andreou, Christos
Zeindler, Jasmin
Oertli, Daniel
Misteli, Heidi
Longterm outcome of anal fistula – A retrospective study
title Longterm outcome of anal fistula – A retrospective study
title_full Longterm outcome of anal fistula – A retrospective study
title_fullStr Longterm outcome of anal fistula – A retrospective study
title_full_unstemmed Longterm outcome of anal fistula – A retrospective study
title_short Longterm outcome of anal fistula – A retrospective study
title_sort longterm outcome of anal fistula – a retrospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162908/
https://www.ncbi.nlm.nih.gov/pubmed/32300218
http://dx.doi.org/10.1038/s41598-020-63541-3
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