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Oligomeric amyloid-β induces early and widespread changes to the proteome in human iPSC-derived neurons
Alzheimer’s disease (AD) is the most common form of dementia globally and is characterized by aberrant accumulations of amyloid-beta (Aβ) and tau proteins. Oligomeric forms of these proteins are believed to be most relevant to disease progression, with oligomeric amyloid-β (oAβ) particularly implica...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162932/ https://www.ncbi.nlm.nih.gov/pubmed/32300132 http://dx.doi.org/10.1038/s41598-020-63398-6 |