Cargando…
Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction
Basilar artery (BA) dolichosis is not uncommon in patients with acute isolated pontine infarction. The effect of this abnormal BA geometrical form on the outcomes of pontine infarction has not been closely examined. This study aims to elucidate whether BA dolichosis contributes to a poor 90-day outc...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162970/ https://www.ncbi.nlm.nih.gov/pubmed/32300126 http://dx.doi.org/10.1038/s41598-020-62873-4 |
_version_ | 1783523129842204672 |
---|---|
author | Cao, Shu-gang Ni, Xiaoxing Wu, Qian He, Jun Cui, Ping Ge, Tingting Li, Yuancheng Wang, Jian Wen’an, X. U. Xia, Mingwu |
author_facet | Cao, Shu-gang Ni, Xiaoxing Wu, Qian He, Jun Cui, Ping Ge, Tingting Li, Yuancheng Wang, Jian Wen’an, X. U. Xia, Mingwu |
author_sort | Cao, Shu-gang |
collection | PubMed |
description | Basilar artery (BA) dolichosis is not uncommon in patients with acute isolated pontine infarction. The effect of this abnormal BA geometrical form on the outcomes of pontine infarction has not been closely examined. This study aims to elucidate whether BA dolichosis contributes to a poor 90-day outcome in acute isolated pontine infarction. A total of 101 patients were enrolled with a median age of 65 years. The BA diameter (p = 0.026), basilar artery length (BAL) (p < 0.001), bending length (BL) (p < 0.001) and the proportion of BA bending (p < 0.001) were significantly higher in the BA dolichosis group. A poor outcome was closely associated with the baseline National Institute of Health Stroke Scale (NIHSS) score (p < 0.001), and BL (p = 0.042) as well as the proportions of BA dolichosis (p = 0.007) and BA bending (p = 0.010) in univariate analysis. Multivariate logistic regression analysis determined that BA dolichosis (adjusted OR = 4.724, 95% CI: 1.481~15.071, p = 0.009) and baseline NIHSS score (adjusted OR = 1.805, 95% CI: 1.296~2.513, p < 0.001) were independently associated with a poor outcome at 90 days. In conclusion, BA dolichosis may be a predictor of concern for a poor 90-day outcome in patients with acute isolated pontine infarction. |
format | Online Article Text |
id | pubmed-7162970 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-71629702020-04-23 Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction Cao, Shu-gang Ni, Xiaoxing Wu, Qian He, Jun Cui, Ping Ge, Tingting Li, Yuancheng Wang, Jian Wen’an, X. U. Xia, Mingwu Sci Rep Article Basilar artery (BA) dolichosis is not uncommon in patients with acute isolated pontine infarction. The effect of this abnormal BA geometrical form on the outcomes of pontine infarction has not been closely examined. This study aims to elucidate whether BA dolichosis contributes to a poor 90-day outcome in acute isolated pontine infarction. A total of 101 patients were enrolled with a median age of 65 years. The BA diameter (p = 0.026), basilar artery length (BAL) (p < 0.001), bending length (BL) (p < 0.001) and the proportion of BA bending (p < 0.001) were significantly higher in the BA dolichosis group. A poor outcome was closely associated with the baseline National Institute of Health Stroke Scale (NIHSS) score (p < 0.001), and BL (p = 0.042) as well as the proportions of BA dolichosis (p = 0.007) and BA bending (p = 0.010) in univariate analysis. Multivariate logistic regression analysis determined that BA dolichosis (adjusted OR = 4.724, 95% CI: 1.481~15.071, p = 0.009) and baseline NIHSS score (adjusted OR = 1.805, 95% CI: 1.296~2.513, p < 0.001) were independently associated with a poor outcome at 90 days. In conclusion, BA dolichosis may be a predictor of concern for a poor 90-day outcome in patients with acute isolated pontine infarction. Nature Publishing Group UK 2020-04-16 /pmc/articles/PMC7162970/ /pubmed/32300126 http://dx.doi.org/10.1038/s41598-020-62873-4 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Cao, Shu-gang Ni, Xiaoxing Wu, Qian He, Jun Cui, Ping Ge, Tingting Li, Yuancheng Wang, Jian Wen’an, X. U. Xia, Mingwu Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction |
title | Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction |
title_full | Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction |
title_fullStr | Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction |
title_full_unstemmed | Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction |
title_short | Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction |
title_sort | basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162970/ https://www.ncbi.nlm.nih.gov/pubmed/32300126 http://dx.doi.org/10.1038/s41598-020-62873-4 |
work_keys_str_mv | AT caoshugang basilararterydolichosisisassociatedwithapoor90dayoutcomeinacuteisolatedpontineinfarction AT nixiaoxing basilararterydolichosisisassociatedwithapoor90dayoutcomeinacuteisolatedpontineinfarction AT wuqian basilararterydolichosisisassociatedwithapoor90dayoutcomeinacuteisolatedpontineinfarction AT hejun basilararterydolichosisisassociatedwithapoor90dayoutcomeinacuteisolatedpontineinfarction AT cuiping basilararterydolichosisisassociatedwithapoor90dayoutcomeinacuteisolatedpontineinfarction AT getingting basilararterydolichosisisassociatedwithapoor90dayoutcomeinacuteisolatedpontineinfarction AT liyuancheng basilararterydolichosisisassociatedwithapoor90dayoutcomeinacuteisolatedpontineinfarction AT wangjian basilararterydolichosisisassociatedwithapoor90dayoutcomeinacuteisolatedpontineinfarction AT wenanxu basilararterydolichosisisassociatedwithapoor90dayoutcomeinacuteisolatedpontineinfarction AT xiamingwu basilararterydolichosisisassociatedwithapoor90dayoutcomeinacuteisolatedpontineinfarction |