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Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction

Basilar artery (BA) dolichosis is not uncommon in patients with acute isolated pontine infarction. The effect of this abnormal BA geometrical form on the outcomes of pontine infarction has not been closely examined. This study aims to elucidate whether BA dolichosis contributes to a poor 90-day outc...

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Autores principales: Cao, Shu-gang, Ni, Xiaoxing, Wu, Qian, He, Jun, Cui, Ping, Ge, Tingting, Li, Yuancheng, Wang, Jian, Wen’an, X. U., Xia, Mingwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162970/
https://www.ncbi.nlm.nih.gov/pubmed/32300126
http://dx.doi.org/10.1038/s41598-020-62873-4
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author Cao, Shu-gang
Ni, Xiaoxing
Wu, Qian
He, Jun
Cui, Ping
Ge, Tingting
Li, Yuancheng
Wang, Jian
Wen’an, X. U.
Xia, Mingwu
author_facet Cao, Shu-gang
Ni, Xiaoxing
Wu, Qian
He, Jun
Cui, Ping
Ge, Tingting
Li, Yuancheng
Wang, Jian
Wen’an, X. U.
Xia, Mingwu
author_sort Cao, Shu-gang
collection PubMed
description Basilar artery (BA) dolichosis is not uncommon in patients with acute isolated pontine infarction. The effect of this abnormal BA geometrical form on the outcomes of pontine infarction has not been closely examined. This study aims to elucidate whether BA dolichosis contributes to a poor 90-day outcome in acute isolated pontine infarction. A total of 101 patients were enrolled with a median age of 65 years. The BA diameter (p = 0.026), basilar artery length (BAL) (p < 0.001), bending length (BL) (p < 0.001) and the proportion of BA bending (p < 0.001) were significantly higher in the BA dolichosis group. A poor outcome was closely associated with the baseline National Institute of Health Stroke Scale (NIHSS) score (p < 0.001), and BL (p = 0.042) as well as the proportions of BA dolichosis (p = 0.007) and BA bending (p = 0.010) in univariate analysis. Multivariate logistic regression analysis determined that BA dolichosis (adjusted OR = 4.724, 95% CI: 1.481~15.071, p = 0.009) and baseline NIHSS score (adjusted OR = 1.805, 95% CI: 1.296~2.513, p < 0.001) were independently associated with a poor outcome at 90 days. In conclusion, BA dolichosis may be a predictor of concern for a poor 90-day outcome in patients with acute isolated pontine infarction.
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spelling pubmed-71629702020-04-23 Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction Cao, Shu-gang Ni, Xiaoxing Wu, Qian He, Jun Cui, Ping Ge, Tingting Li, Yuancheng Wang, Jian Wen’an, X. U. Xia, Mingwu Sci Rep Article Basilar artery (BA) dolichosis is not uncommon in patients with acute isolated pontine infarction. The effect of this abnormal BA geometrical form on the outcomes of pontine infarction has not been closely examined. This study aims to elucidate whether BA dolichosis contributes to a poor 90-day outcome in acute isolated pontine infarction. A total of 101 patients were enrolled with a median age of 65 years. The BA diameter (p = 0.026), basilar artery length (BAL) (p < 0.001), bending length (BL) (p < 0.001) and the proportion of BA bending (p < 0.001) were significantly higher in the BA dolichosis group. A poor outcome was closely associated with the baseline National Institute of Health Stroke Scale (NIHSS) score (p < 0.001), and BL (p = 0.042) as well as the proportions of BA dolichosis (p = 0.007) and BA bending (p = 0.010) in univariate analysis. Multivariate logistic regression analysis determined that BA dolichosis (adjusted OR = 4.724, 95% CI: 1.481~15.071, p = 0.009) and baseline NIHSS score (adjusted OR = 1.805, 95% CI: 1.296~2.513, p < 0.001) were independently associated with a poor outcome at 90 days. In conclusion, BA dolichosis may be a predictor of concern for a poor 90-day outcome in patients with acute isolated pontine infarction. Nature Publishing Group UK 2020-04-16 /pmc/articles/PMC7162970/ /pubmed/32300126 http://dx.doi.org/10.1038/s41598-020-62873-4 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Cao, Shu-gang
Ni, Xiaoxing
Wu, Qian
He, Jun
Cui, Ping
Ge, Tingting
Li, Yuancheng
Wang, Jian
Wen’an, X. U.
Xia, Mingwu
Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction
title Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction
title_full Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction
title_fullStr Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction
title_full_unstemmed Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction
title_short Basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction
title_sort basilar artery dolichosis is associated with a poor 90-day outcome in acute isolated pontine infarction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7162970/
https://www.ncbi.nlm.nih.gov/pubmed/32300126
http://dx.doi.org/10.1038/s41598-020-62873-4
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