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Enhancing the therapeutic effects of in vitro targeted radionuclide therapy of 3D multicellular tumor spheroids using the novel stapled MDM2/X-p53 antagonist PM2

BACKGROUND: Precision therapeutics continuously make advances in cancer therapy, and a field of growing interest is the combination of targeted radionuclide therapy (TRNT) with potential radiosensitizing agents. This study evaluated whether the effects of in vitro TRNT, using the (177)Lu-labeled ant...

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Detalles Bibliográficos
Autores principales: Mortensen, Anja C. L., Morin, Eric, Brown, Christopher J., Lane, David P., Nestor, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163001/
https://www.ncbi.nlm.nih.gov/pubmed/32300907
http://dx.doi.org/10.1186/s13550-020-0613-7