Comparison of Clinically Relevant Oncolytic Virus Platforms for Enhancing T Cell Therapy of Solid Tumors

Despite some promising results, the majority of patients do not benefit from T cell therapies, as tumors prevent T cells from entering the tumor, shut down their activity, or downregulate key antigens. Due to their nature and mechanism of action, oncolytic viruses have features that can help overcom...

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Detalles Bibliográficos
Autores principales: Cervera-Carrascon, Victor, Quixabeira, Dafne C.A., Havunen, Riikka, Santos, Joao M., Kutvonen, Emma, Clubb, James H.A., Siurala, Mikko, Heiniö, Camilla, Zafar, Sadia, Koivula, Teija, Lumen, Dave, Vaha, Marjo, Garcia-Horsman, Arturo, Airaksinen, Anu J., Sorsa, Suvi, Anttila, Marjukka, Hukkanen, Veijo, Kanerva, Anna, Hemminki, Akseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163046/
https://www.ncbi.nlm.nih.gov/pubmed/32322662
http://dx.doi.org/10.1016/j.omto.2020.03.003

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