IRF5 Promotes Influenza Virus-Induced Inflammatory Responses in Human Induced Pluripotent Stem Cell-Derived Myeloid Cells and Murine Models

Recognition of influenza A virus (IAV) by the innate immune system triggers pathways that restrict viral replication, activate innate immune cells, and regulate adaptive immunity. However, excessive innate immune activation can exaggerate disease. The pathways promoting excessive activation are inco...

Descripción completa

Detalles Bibliográficos
Autores principales: Forbester, Jessica L., Clement, Mathew, Wellington, Dannielle, Yeung, Amy, Dimonte, Sandra, Marsden, Morgan, Chapman, Lucy, Coomber, Eve L., Tolley, Charlotte, Lees, Emily, Hale, Christine, Clare, Simon, Udalova, Irina, Dong, Tao, Dougan, Gordon, Humphreys, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Pathogenesis and Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163152/
https://www.ncbi.nlm.nih.gov/pubmed/32075938
http://dx.doi.org/10.1128/JVI.00121-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163152/
https://www.ncbi.nlm.nih.gov/pubmed/32075938
http://dx.doi.org/10.1128/JVI.00121-20

Ejemplares similares