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Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy

Simultaneous primary cancers are rare in the oropharynx. This report describes the first reported case of a collision tumor of squamous cell and adenoid cystic carcinoma in the soft palate. The patient was immunosuppressed with a history of liver transplantation, smoking and heavy alcohol drinking....

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Autores principales: Reshko, Leonid, Khan, Zafrulla, Sowards, Keith T, Jordan, Adrienne, Silverman, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163338/
https://www.ncbi.nlm.nih.gov/pubmed/32313738
http://dx.doi.org/10.7759/cureus.7297
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author Reshko, Leonid
Khan, Zafrulla
Sowards, Keith T
Jordan, Adrienne
Silverman, Craig
author_facet Reshko, Leonid
Khan, Zafrulla
Sowards, Keith T
Jordan, Adrienne
Silverman, Craig
author_sort Reshko, Leonid
collection PubMed
description Simultaneous primary cancers are rare in the oropharynx. This report describes the first reported case of a collision tumor of squamous cell and adenoid cystic carcinoma in the soft palate. The patient was immunosuppressed with a history of liver transplantation, smoking and heavy alcohol drinking. He was treated with wide local excision followed by adjuvant radiotherapy with surface acrylic mold brachytherapy. This technique was used instead of external beam radiotherapy in order to minimize toxicity. The patient tolerated the treatment well and with the only acute grade two mucositis at the soft palate and minimal late toxicity. There is no evidence of disease recurrence and the patient continues to maintain excellent quality of speech and swallowing 14 months after treatment completion.
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spelling pubmed-71633382020-04-20 Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy Reshko, Leonid Khan, Zafrulla Sowards, Keith T Jordan, Adrienne Silverman, Craig Cureus Otolaryngology Simultaneous primary cancers are rare in the oropharynx. This report describes the first reported case of a collision tumor of squamous cell and adenoid cystic carcinoma in the soft palate. The patient was immunosuppressed with a history of liver transplantation, smoking and heavy alcohol drinking. He was treated with wide local excision followed by adjuvant radiotherapy with surface acrylic mold brachytherapy. This technique was used instead of external beam radiotherapy in order to minimize toxicity. The patient tolerated the treatment well and with the only acute grade two mucositis at the soft palate and minimal late toxicity. There is no evidence of disease recurrence and the patient continues to maintain excellent quality of speech and swallowing 14 months after treatment completion. Cureus 2020-03-17 /pmc/articles/PMC7163338/ /pubmed/32313738 http://dx.doi.org/10.7759/cureus.7297 Text en Copyright © 2020, Reshko et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Otolaryngology
Reshko, Leonid
Khan, Zafrulla
Sowards, Keith T
Jordan, Adrienne
Silverman, Craig
Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy
title Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy
title_full Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy
title_fullStr Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy
title_full_unstemmed Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy
title_short Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy
title_sort squamous cell and adenoid cystic carcinoma collision tumor of the soft palate treated with surface mold brachytherapy
topic Otolaryngology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163338/
https://www.ncbi.nlm.nih.gov/pubmed/32313738
http://dx.doi.org/10.7759/cureus.7297
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