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Placental transporter‐mediated drug interactions and offspring congenital anomalies

AIMS: P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) are efflux transporters expressed in the placenta, limiting their substrates from reaching the foetus. Our aim was to investigate if concomitant prenatal exposure to several substrates or inhibitors of these transporters increas...

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Detalles Bibliográficos
Autores principales: Ellfolk, Maria, Tornio, Aleksi, Niemi, Mikko, Leinonen, Maarit K., Lahesmaa‐Korpinen, Anna‐Maria, Malm, Heli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163376/
https://www.ncbi.nlm.nih.gov/pubmed/31823387
http://dx.doi.org/10.1111/bcp.14191