Up‐regulation of indoleamine 2,3‐dioxygenase 1 (IDO1) expression and catalytic activity is associated with immunosuppression and poor prognosis in penile squamous cell carcinoma patients

BACKGROUND: Indoleamine 2,3‐dioxygenase 1 (IDO1) and tryptophan (Trp) catabolism have been demonstrated to play an important role in tumor immunosuppression. This study examined the expression and catalytic activity of IDO1 in penile squamous cell carcinoma (PSCC) and explored their clinical signifi...

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Detalles Bibliográficos
Autores principales: Zhou, Qiang‐hua, Han, Hui, Lu, Jia‐bin, Liu, Ting‐yu, Huang, Kang‐bo, Deng, Chuang‐zhong, Li, Zai‐shang, Chen, Jie‐ping, Yao, Kai, Qin, Zi‐ke, Liu, Zhuo‐wei, Li, Yong‐hong, Guo, Sheng‐jie, Ye, Yun‐lin, Zhou, Fang‐jian, Liu, Ran‐yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163927/
https://www.ncbi.nlm.nih.gov/pubmed/32125093
http://dx.doi.org/10.1002/cac2.12001

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