EphB4/ TNFR2/ERK/MAPK signaling pathway comprises a signaling axis to mediate the positive effect of TNF-α on osteogenic differentiation

BACKGROUND: Low concentrations of tumor necrosis factor-alpha (TNF-α) and its receptor TNFR2 are both reported to promote osteogenic differentiation of osteoblast precursor cells. Moreover, low concentrations of TNF-α up-regulate the expression of EphB4. However, the molecular mechanisms underlying...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Yang, Chengzhe, Ge, Shaohua, Wang, Limei, Zhang, Jin, Yang, Pishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164363/
https://www.ncbi.nlm.nih.gov/pubmed/32299362
http://dx.doi.org/10.1186/s12860-020-00273-2

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