Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2

Severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) causes the infectious disease COVID-19 (coronavirus disease 2019), which was first reported in Wuhan, China, in December 2019. Despite extensive efforts to control the disease, COVID-19 has now spread to more than 100 countries and caused...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Jianzhong, Wen, Zhiyuan, Zhong, Gongxun, Yang, Huanliang, Wang, Chong, Huang, Baoying, Liu, Renqiang, He, Xijun, Shuai, Lei, Sun, Ziruo, Zhao, Yubo, Liu, Peipei, Liang, Libin, Cui, Pengfei, Wang, Jinliang, Zhang, Xianfeng, Guan, Yuntao, Tan, Wenjie, Wu, Guizhen, Chen, Hualan, Bu, Zhigao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164390/
https://www.ncbi.nlm.nih.gov/pubmed/32269068
http://dx.doi.org/10.1126/science.abb7015
_version_ 1783523284207271936
author Shi, Jianzhong
Wen, Zhiyuan
Zhong, Gongxun
Yang, Huanliang
Wang, Chong
Huang, Baoying
Liu, Renqiang
He, Xijun
Shuai, Lei
Sun, Ziruo
Zhao, Yubo
Liu, Peipei
Liang, Libin
Cui, Pengfei
Wang, Jinliang
Zhang, Xianfeng
Guan, Yuntao
Tan, Wenjie
Wu, Guizhen
Chen, Hualan
Bu, Zhigao
author_facet Shi, Jianzhong
Wen, Zhiyuan
Zhong, Gongxun
Yang, Huanliang
Wang, Chong
Huang, Baoying
Liu, Renqiang
He, Xijun
Shuai, Lei
Sun, Ziruo
Zhao, Yubo
Liu, Peipei
Liang, Libin
Cui, Pengfei
Wang, Jinliang
Zhang, Xianfeng
Guan, Yuntao
Tan, Wenjie
Wu, Guizhen
Chen, Hualan
Bu, Zhigao
author_sort Shi, Jianzhong
collection PubMed
description Severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) causes the infectious disease COVID-19 (coronavirus disease 2019), which was first reported in Wuhan, China, in December 2019. Despite extensive efforts to control the disease, COVID-19 has now spread to more than 100 countries and caused a global pandemic. SARS-CoV-2 is thought to have originated in bats; however, the intermediate animal sources of the virus are unknown. In this study, we investigated the susceptibility of ferrets and animals in close contact with humans to SARS-CoV-2. We found that SARS-CoV-2 replicates poorly in dogs, pigs, chickens, and ducks, but ferrets and cats are permissive to infection. Additionally, cats are susceptible to airborne transmission. Our study provides insights into the animal models for SARS-CoV-2 and animal management for COVID-19 control.
format Online
Article
Text
id pubmed-7164390
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher American Association for the Advancement of Science
record_format MEDLINE/PubMed
spelling pubmed-71643902020-04-20 Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2 Shi, Jianzhong Wen, Zhiyuan Zhong, Gongxun Yang, Huanliang Wang, Chong Huang, Baoying Liu, Renqiang He, Xijun Shuai, Lei Sun, Ziruo Zhao, Yubo Liu, Peipei Liang, Libin Cui, Pengfei Wang, Jinliang Zhang, Xianfeng Guan, Yuntao Tan, Wenjie Wu, Guizhen Chen, Hualan Bu, Zhigao Science Reports Severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) causes the infectious disease COVID-19 (coronavirus disease 2019), which was first reported in Wuhan, China, in December 2019. Despite extensive efforts to control the disease, COVID-19 has now spread to more than 100 countries and caused a global pandemic. SARS-CoV-2 is thought to have originated in bats; however, the intermediate animal sources of the virus are unknown. In this study, we investigated the susceptibility of ferrets and animals in close contact with humans to SARS-CoV-2. We found that SARS-CoV-2 replicates poorly in dogs, pigs, chickens, and ducks, but ferrets and cats are permissive to infection. Additionally, cats are susceptible to airborne transmission. Our study provides insights into the animal models for SARS-CoV-2 and animal management for COVID-19 control. American Association for the Advancement of Science 2020-05-29 2020-04-08 /pmc/articles/PMC7164390/ /pubmed/32269068 http://dx.doi.org/10.1126/science.abb7015 Text en Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). http://creativecommons.org/licenses/by/4.0/ https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.
spellingShingle Reports
Shi, Jianzhong
Wen, Zhiyuan
Zhong, Gongxun
Yang, Huanliang
Wang, Chong
Huang, Baoying
Liu, Renqiang
He, Xijun
Shuai, Lei
Sun, Ziruo
Zhao, Yubo
Liu, Peipei
Liang, Libin
Cui, Pengfei
Wang, Jinliang
Zhang, Xianfeng
Guan, Yuntao
Tan, Wenjie
Wu, Guizhen
Chen, Hualan
Bu, Zhigao
Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2
title Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2
title_full Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2
title_fullStr Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2
title_full_unstemmed Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2
title_short Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS–coronavirus 2
title_sort susceptibility of ferrets, cats, dogs, and other domesticated animals to sars–coronavirus 2
topic Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164390/
https://www.ncbi.nlm.nih.gov/pubmed/32269068
http://dx.doi.org/10.1126/science.abb7015
work_keys_str_mv AT shijianzhong susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT wenzhiyuan susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT zhonggongxun susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT yanghuanliang susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT wangchong susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT huangbaoying susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT liurenqiang susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT hexijun susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT shuailei susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT sunziruo susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT zhaoyubo susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT liupeipei susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT lianglibin susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT cuipengfei susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT wangjinliang susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT zhangxianfeng susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT guanyuntao susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT tanwenjie susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT wuguizhen susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT chenhualan susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2
AT buzhigao susceptibilityofferretscatsdogsandotherdomesticatedanimalstosarscoronavirus2

Ejemplares similares