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Mechanopharmacology and Synergistic Relaxation of Airway Smooth Muscle

Asthmatic airways are stiffer than normal. We have shown that the cytoskeletal passive stiffness of airway smooth muscle (ASM) can be regulated by intracellular signaling pathways, especially those associated with Rho kinase (ROCK). We have also shown that an oscillatory strain reduces the passive s...

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Detalles Bibliográficos
Autores principales:	Wang, Lu, Chitano, Pasquale, Paré, Peter D., Seow, Chun Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Mechanical Engineers 2019
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164492/ https://www.ncbi.nlm.nih.gov/pubmed/32328573 http://dx.doi.org/10.1115/1.4042477

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