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Superficial Siderosis Misdiagnosed As Parkinson’s Disease in a 70-year-old Male Breast Cancer Survivor

A 70-year-old African American male with a history of hypertension, congestive heart failure, breast cancer status-post six rounds of doxorubicin/cyclophosphamide, and Parkinson’s disease managed with carbidopa/levodopa presented to the emergency department with bilateral hearing loss and ataxia. Th...

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Detalles Bibliográficos
Autores principales: Bordes, Stephen J, Bang, Katrina E, Tubbs, R. Shane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164556/
https://www.ncbi.nlm.nih.gov/pubmed/32313748
http://dx.doi.org/10.7759/cureus.7307
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author Bordes, Stephen J
Bang, Katrina E
Tubbs, R. Shane
author_facet Bordes, Stephen J
Bang, Katrina E
Tubbs, R. Shane
author_sort Bordes, Stephen J
collection PubMed
description A 70-year-old African American male with a history of hypertension, congestive heart failure, breast cancer status-post six rounds of doxorubicin/cyclophosphamide, and Parkinson’s disease managed with carbidopa/levodopa presented to the emergency department with bilateral hearing loss and ataxia. The patient was admitted and evaluated for possible traumatic, oncological, and pharmacological etiologies. Further investigation revealed hypointensities along the cerebellar folia and basal cisterns on MRI in addition to the two-year history of progressive bilateral hearing loss and gait ataxia. In view of these findings, the patient was diagnosed with superficial siderosis and Parkinson’s medications were discontinued. Superficial siderosis should be considered as a diagnosis in cases of bilateral hearing loss and ataxia in patients with history of anticoagulation and risk factors for prior cerebrovascular accidents or head trauma.
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spelling pubmed-71645562020-04-20 Superficial Siderosis Misdiagnosed As Parkinson’s Disease in a 70-year-old Male Breast Cancer Survivor Bordes, Stephen J Bang, Katrina E Tubbs, R. Shane Cureus Internal Medicine A 70-year-old African American male with a history of hypertension, congestive heart failure, breast cancer status-post six rounds of doxorubicin/cyclophosphamide, and Parkinson’s disease managed with carbidopa/levodopa presented to the emergency department with bilateral hearing loss and ataxia. The patient was admitted and evaluated for possible traumatic, oncological, and pharmacological etiologies. Further investigation revealed hypointensities along the cerebellar folia and basal cisterns on MRI in addition to the two-year history of progressive bilateral hearing loss and gait ataxia. In view of these findings, the patient was diagnosed with superficial siderosis and Parkinson’s medications were discontinued. Superficial siderosis should be considered as a diagnosis in cases of bilateral hearing loss and ataxia in patients with history of anticoagulation and risk factors for prior cerebrovascular accidents or head trauma. Cureus 2020-03-18 /pmc/articles/PMC7164556/ /pubmed/32313748 http://dx.doi.org/10.7759/cureus.7307 Text en Copyright © 2020, Bordes et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Bordes, Stephen J
Bang, Katrina E
Tubbs, R. Shane
Superficial Siderosis Misdiagnosed As Parkinson’s Disease in a 70-year-old Male Breast Cancer Survivor
title Superficial Siderosis Misdiagnosed As Parkinson’s Disease in a 70-year-old Male Breast Cancer Survivor
title_full Superficial Siderosis Misdiagnosed As Parkinson’s Disease in a 70-year-old Male Breast Cancer Survivor
title_fullStr Superficial Siderosis Misdiagnosed As Parkinson’s Disease in a 70-year-old Male Breast Cancer Survivor
title_full_unstemmed Superficial Siderosis Misdiagnosed As Parkinson’s Disease in a 70-year-old Male Breast Cancer Survivor
title_short Superficial Siderosis Misdiagnosed As Parkinson’s Disease in a 70-year-old Male Breast Cancer Survivor
title_sort superficial siderosis misdiagnosed as parkinson’s disease in a 70-year-old male breast cancer survivor
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164556/
https://www.ncbi.nlm.nih.gov/pubmed/32313748
http://dx.doi.org/10.7759/cureus.7307
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