Podocyte RNA sequencing reveals Wnt- and ECM-associated genes as central in FSGS

Loss of podocyte differentiation can cause nephrotic-range proteinuria and Focal and Segmental Glomerulosclerosis (FSGS). As specific therapy is still lacking, FSGS frequently progresses to end-stage renal disease. The exact molecular mechanisms of FSGS and gene expression changes in podocytes are c...

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Detalles Bibliográficos
Autores principales: Bukosza, Eva Nora, Kratochwill, Klaus, Kornauth, Christoph, Schachner, Helga, Aufricht, Christoph, Gebeshuber, Christoph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164636/
https://www.ncbi.nlm.nih.gov/pubmed/32302353
http://dx.doi.org/10.1371/journal.pone.0231898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164636/
https://www.ncbi.nlm.nih.gov/pubmed/32302353
http://dx.doi.org/10.1371/journal.pone.0231898

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