Highly efficient serum-free manipulation of miRNA in human NK cells without loss of viability or phenotypic alterations is accomplished with TransIT-TKO

Natural killer (NK) cells are innate lymphocytes with functions that include target cell killing, inflammation and regulation. NK cells integrate incoming activating and inhibitory signals through an array of germline-encoded receptors to gauge the health of neighbouring cells. The reactive potentia...

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Detalles Bibliográficos
Autores principales: Hargreaves, Breanna K. V., Roberts, Sarah E., Derfalvi, Beata, Boudreau, Jeanette E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164639/
https://www.ncbi.nlm.nih.gov/pubmed/32302338
http://dx.doi.org/10.1371/journal.pone.0231664