COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities

Mostrar otras versiones (1)

The coronavirus disease-2019 (COVID-19) pandemic has resulted in a proliferation of clinical trials designed to slow the spread of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Many therapeutic agents that are being used to treat patients with COVID-19 are repurposed treatments for i...

Descripción completa

Detalles Bibliográficos
Autores principales: Ky, Bonnie, Mann, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
State-of-the-Art Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164888/
https://www.ncbi.nlm.nih.gov/pubmed/32313885
http://dx.doi.org/10.1016/j.jaccao.2020.04.002
_version_ 1783523373922385920
author Ky, Bonnie
Mann, Douglas L.
author_facet Ky, Bonnie
Mann, Douglas L.
author_sort Ky, Bonnie
collection PubMed
description The coronavirus disease-2019 (COVID-19) pandemic has resulted in a proliferation of clinical trials designed to slow the spread of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Many therapeutic agents that are being used to treat patients with COVID-19 are repurposed treatments for influenza, Ebola, or for malaria that were developed decades ago and are unlikely to be familiar to the cardiovascular and cardio-oncology communities. Here, we provide a foundation for cardiovascular and cardio-oncology physicians on the front line providing care to patients with COVID-19, so that they may better understand the emerging cardiovascular epidemiology and the biological rationale for the clinical trials that are ongoing for the treatment of patients with COVID-19.
format Online
Article
Text
id pubmed-7164888
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-71648882020-04-20 COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities Ky, Bonnie Mann, Douglas L. JACC CardioOncol State-of-the-Art Review The coronavirus disease-2019 (COVID-19) pandemic has resulted in a proliferation of clinical trials designed to slow the spread of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Many therapeutic agents that are being used to treat patients with COVID-19 are repurposed treatments for influenza, Ebola, or for malaria that were developed decades ago and are unlikely to be familiar to the cardiovascular and cardio-oncology communities. Here, we provide a foundation for cardiovascular and cardio-oncology physicians on the front line providing care to patients with COVID-19, so that they may better understand the emerging cardiovascular epidemiology and the biological rationale for the clinical trials that are ongoing for the treatment of patients with COVID-19. Elsevier 2020-04-17 /pmc/articles/PMC7164888/ /pubmed/32313885 http://dx.doi.org/10.1016/j.jaccao.2020.04.002 Text en © 2020 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle State-of-the-Art Review
Ky, Bonnie
Mann, Douglas L.
COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities
title COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities
title_full COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities
title_fullStr COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities
title_full_unstemmed COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities
title_short COVID-19 Clinical Trials: A Primer for the Cardiovascular and Cardio-Oncology Communities
title_sort covid-19 clinical trials: a primer for the cardiovascular and cardio-oncology communities
topic State-of-the-Art Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164888/
https://www.ncbi.nlm.nih.gov/pubmed/32313885
http://dx.doi.org/10.1016/j.jaccao.2020.04.002
work_keys_str_mv AT kybonnie covid19clinicaltrialsaprimerforthecardiovascularandcardiooncologycommunities
AT manndouglasl covid19clinicaltrialsaprimerforthecardiovascularandcardiooncologycommunities

Ejemplares similares