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Commensal epitopes drive differentiation of colonic T(regs)
The gut microbiome is the largest source of intrinsic non–self-antigens that are continuously sensed by the immune system but typically do not elicit lymphocyte responses. CD4(+) T cells are critical to sustain uninterrupted tolerance to microbial antigens and to prevent intestinal inflammation. How...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164940/ https://www.ncbi.nlm.nih.gov/pubmed/32494613 http://dx.doi.org/10.1126/sciadv.aaz3186 |