Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression

The melanoma-associated antigen family A (MAGEA) antigens are expressed in a wide variety of malignant tumors but not in adult somatic cells, rendering them attractive targets for cancer immunotherapy. Here we show that a number of cancer-associated MAGEA mutants that undergo proteasome-dependent de...

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Detalles Bibliográficos
Autores principales: Tsang, Yiu Huen, Wang, Yumeng, Kong, Kathleen, Grzeskowiak, Caitlin, Zagorodna, Oksana, Dogruluk, Turgut, Lu, Hengyu, Villafane, Nicole, Bhavana, Venkata Hemanjani, Moreno, Daniela, Elsea, Sarah H, Liang, Han, Mills, Gordon B, Scott, Kenneth L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164953/
https://www.ncbi.nlm.nih.gov/pubmed/32270762
http://dx.doi.org/10.7554/eLife.48963

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