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Polygenic risk scores of several subtypes of epilepsies in a founder population
OBJECTIVE: Polygenic risk scores (PRSs) are used to quantify the cumulative effects of a number of genetic variants, which may individually have a very small effect on susceptibility to a disease; we used PRSs to better understand the genetic contribution to common epilepsy and its subtypes. METHODS...
Autores principales: | Moreau, Claudia, Rébillard, Rose-Marie, Wolking, Stefan, Michaud, Jacques, Tremblay, Frédérique, Girard, Alexandre, Bouchard, Joanie, Minassian, Berge, Laprise, Catherine, Cossette, Patrick, Girard, Simon L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164970/ https://www.ncbi.nlm.nih.gov/pubmed/32337343 http://dx.doi.org/10.1212/NXG.0000000000000416 |
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