Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection

Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous amounts of economic losses to the swine industry for more than three decades, but its control is still unsatisfactory. A significant amount of information is available for host cell-virus interactions during infection,...

Descripción completa

Detalles Bibliográficos
Autores principales: An, Tong-Qing, Li, Jiang-Nan, Su, Chia-Ming, Yoo, Dongwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165118/
https://www.ncbi.nlm.nih.gov/pubmed/32311386
http://dx.doi.org/10.1016/j.virusres.2020.197980
_version_ 1783523412364230656
author An, Tong-Qing
Li, Jiang-Nan
Su, Chia-Ming
Yoo, Dongwan
author_facet An, Tong-Qing
Li, Jiang-Nan
Su, Chia-Ming
Yoo, Dongwan
author_sort An, Tong-Qing
collection PubMed
description Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous amounts of economic losses to the swine industry for more than three decades, but its control is still unsatisfactory. A significant amount of information is available for host cell-virus interactions during infection, and it is evident that PRRSV has evolved to equip various strategies to disrupt the host antiviral system and provide favorable conditions for survival. The current study reviews viral strategies for modulations of cellular processes including innate immunity, apoptosis, microRNAs, inflammatory cytokines, and other cellular pathways.
format Online
Article
Text
id pubmed-7165118
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Published by Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-71651182020-04-20 Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection An, Tong-Qing Li, Jiang-Nan Su, Chia-Ming Yoo, Dongwan Virus Res Article Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous amounts of economic losses to the swine industry for more than three decades, but its control is still unsatisfactory. A significant amount of information is available for host cell-virus interactions during infection, and it is evident that PRRSV has evolved to equip various strategies to disrupt the host antiviral system and provide favorable conditions for survival. The current study reviews viral strategies for modulations of cellular processes including innate immunity, apoptosis, microRNAs, inflammatory cytokines, and other cellular pathways. Published by Elsevier B.V. 2020-09 2020-04-18 /pmc/articles/PMC7165118/ /pubmed/32311386 http://dx.doi.org/10.1016/j.virusres.2020.197980 Text en © 2020 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
An, Tong-Qing
Li, Jiang-Nan
Su, Chia-Ming
Yoo, Dongwan
Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection
title Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection
title_full Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection
title_fullStr Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection
title_full_unstemmed Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection
title_short Molecular and Cellular Mechanisms for PRRSV Pathogenesis and Host Response to Infection
title_sort molecular and cellular mechanisms for prrsv pathogenesis and host response to infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165118/
https://www.ncbi.nlm.nih.gov/pubmed/32311386
http://dx.doi.org/10.1016/j.virusres.2020.197980
work_keys_str_mv AT antongqing molecularandcellularmechanismsforprrsvpathogenesisandhostresponsetoinfection
AT lijiangnan molecularandcellularmechanismsforprrsvpathogenesisandhostresponsetoinfection
AT suchiaming molecularandcellularmechanismsforprrsvpathogenesisandhostresponsetoinfection
AT yoodongwan molecularandcellularmechanismsforprrsvpathogenesisandhostresponsetoinfection

Ejemplares similares