Cargando…
The regulatory mechanism and biological significance of the Snail-miR590-VEGFR-NRP1 axis in the angiogenesis, growth and metastasis of gastric cancer
Vascular endothelial growth factor receptor (VEGFR) and neuropilins (NRPs), a co-receptor of VEGF, play a key role in the formation and development of blood vessels and in tumour growth and metastasis. However, whether VEGFR1/2 and NRP1 are regulated by the same upstream mechanism is unclear, especi...
Autores principales: | Mei, Bin, Chen, Jiajie, Yang, Ni, Peng, Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165172/ https://www.ncbi.nlm.nih.gov/pubmed/32303680 http://dx.doi.org/10.1038/s41419-020-2428-x |
Ejemplares similares
-
Vascular NRP2 triggers PNET angiogenesis by activating the SSH1-cofilin axis
por: Luo, Xi, et al.
Publicado: (2020) -
The SNAIL/miR-128 axis regulated growth, invasion, metastasis, and epithelial-to-mesenchymal transition of gastric cancer
por: Yu, Wei-Wei, et al.
Publicado: (2017) -
MiR-590-5p inhibits colorectal cancer angiogenesis and metastasis by regulating nuclear factor 90/vascular endothelial growth factor A axis
por: Zhou, Qingxin, et al.
Publicado: (2016) -
An Essential NRP1-Mediated Role for Tagln2 in Gastric Cancer Angiogenesis
por: Jin, Hongwei, et al.
Publicado: (2021) -
Impaired AGO2/miR-185-3p/NRP1 axis promotes colorectal cancer metastasis
por: Liu, Xisheng, et al.
Publicado: (2021)