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Inhibition of BRD4 prevents proliferation and epithelial–mesenchymal transition in renal cell carcinoma via NLRP3 inflammasome-induced pyroptosis
BRD4 has long been implicated in many different pathological processes, in particular, the development of cancer and inflammation. Pyroptosis is a newly recognized type of inflammatory programmed cell death. However, the correlation between BRD4 and pyroptosis in renal cell carcinoma (RCC) remains e...
Autores principales: | Tan, Yi-Fan, Wang, Min, Chen, Zhi-Yuan, Wang, Lei, Liu, Xiu-Heng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165180/ https://www.ncbi.nlm.nih.gov/pubmed/32303673 http://dx.doi.org/10.1038/s41419-020-2431-2 |
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