Nonclassical nuclear localization signals mediate nuclear import of CIRBP

The specific interaction of importins with nuclear localization signals (NLSs) of cargo proteins not only mediates nuclear import but also, prevents their aberrant phase separation and stress granule recruitment in the cytoplasm. The importin Transportin-1 (TNPO1) plays a key role in the (patho-)phy...

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Detalles Bibliográficos
Autores principales: Bourgeois, Benjamin, Hutten, Saskia, Gottschalk, Benjamin, Hofweber, Mario, Richter, Gesa, Sternat, Julia, Abou-Ajram, Claudia, Göbl, Christoph, Leitinger, Gerd, Graier, Wolfgang F., Dormann, Dorothee, Madl, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165476/
https://www.ncbi.nlm.nih.gov/pubmed/32234784
http://dx.doi.org/10.1073/pnas.1918944117

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