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Dissociation of somatostatin and parvalbumin interneurons circuit dysfunctions underlying hippocampal theta and gamma oscillations impaired by amyloid β oligomers in vivo

Accumulation of amyloid β oligomers (AβO) in Alzheimer’s disease (AD) impairs hippocampal theta and gamma oscillations. These oscillations are important in memory functions and depend on distinct subtypes of hippocampal interneurons such as somatostatin-positive (SST) and parvalbumin-positive (PV) i...

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Detalles Bibliográficos
Autores principales: Chung, Hyowon, Park, Kyerl, Jang, Hyun Jae, Kohl, Michael M., Kwag, Jeehyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166204/
https://www.ncbi.nlm.nih.gov/pubmed/32107637
http://dx.doi.org/10.1007/s00429-020-02044-3