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Rectal and Bladder Dose Measurements in the Intracavitary Applications of Cervical Cancer Treatment with HDR Afterloading System: Comparison of TPS Data with MOSFET Detector

BACKGROUND: Intracavitary brachytherapy plays a major role in management of cervical carcinoma. Assessment of dose received by OAR’s therefore becomes crucial for the estimation of radiation toxicities in HDR brachytherapy. OBJECTIVE: Purpose of this study is to evaluate the role of in vivo dosimetr...

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Autores principales: N., Singh, S., Ahamed, A., Sinha, S., Srivastava, N. K., Painuly, A., Mandal, S. N., Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166216/
https://www.ncbi.nlm.nih.gov/pubmed/32337180
http://dx.doi.org/10.31661/jbpe.v0i0.1065
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author N., Singh
S., Ahamed
A., Sinha
S., Srivastava
N. K., Painuly
A., Mandal
S. N., Prasad
author_facet N., Singh
S., Ahamed
A., Sinha
S., Srivastava
N. K., Painuly
A., Mandal
S. N., Prasad
author_sort N., Singh
collection PubMed
description BACKGROUND: Intracavitary brachytherapy plays a major role in management of cervical carcinoma. Assessment of dose received by OAR’s therefore becomes crucial for the estimation of radiation toxicities in HDR brachytherapy. OBJECTIVE: Purpose of this study is to evaluate the role of in vivo dosimetry in HDR brachytherapy and to compare actual doses delivered to OAR’ s with those calculated during treatment planning. MATERIAL AND METHODS: In this retrospective study, 50 patients of cervical carcinoma were treated by Microselectron HDR. Out of 50 patients, 26 were treated with a dose of 7 Gy and 24 with a dose of 9 Gy, prescribed to point A. Brachytherapy planning and evaluation of dose to bladder and rectum was done on TPS & in vivo dosimetry was performed using portable MOSFET. RESULTS: Calibration factors calculated for both dosimeters are almost equal and are 0.984 cGy/mV and 1.0895 cGy/mV. For bladder, dose deviation was found to be within ± 5% in 28 patients, ± 5-10% in 14 patients, ± 10-15% in 4 patients. Deviation between TPS-calculated dose and dose measured by MOSFET for rectum was within ± 5% in 31 patients, ± 5–10% in 8 patients, and ± 10–15% in 7 patients. CONCLUSION: TPS calculated doses were slightly higher than that measured by MOSFET. The use of small size MOSFET dosimeter is an efficient method for accurately measuring doses in high-dose gradient fields typically seen in brachytherapy. Therefore, to reduce the risk of large errors in dose delivery, in vivo dosimetry can be done in addition to TPS computations.
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spelling pubmed-71662162020-04-24 Rectal and Bladder Dose Measurements in the Intracavitary Applications of Cervical Cancer Treatment with HDR Afterloading System: Comparison of TPS Data with MOSFET Detector N., Singh S., Ahamed A., Sinha S., Srivastava N. K., Painuly A., Mandal S. N., Prasad J Biomed Phys Eng Original Article BACKGROUND: Intracavitary brachytherapy plays a major role in management of cervical carcinoma. Assessment of dose received by OAR’s therefore becomes crucial for the estimation of radiation toxicities in HDR brachytherapy. OBJECTIVE: Purpose of this study is to evaluate the role of in vivo dosimetry in HDR brachytherapy and to compare actual doses delivered to OAR’ s with those calculated during treatment planning. MATERIAL AND METHODS: In this retrospective study, 50 patients of cervical carcinoma were treated by Microselectron HDR. Out of 50 patients, 26 were treated with a dose of 7 Gy and 24 with a dose of 9 Gy, prescribed to point A. Brachytherapy planning and evaluation of dose to bladder and rectum was done on TPS & in vivo dosimetry was performed using portable MOSFET. RESULTS: Calibration factors calculated for both dosimeters are almost equal and are 0.984 cGy/mV and 1.0895 cGy/mV. For bladder, dose deviation was found to be within ± 5% in 28 patients, ± 5-10% in 14 patients, ± 10-15% in 4 patients. Deviation between TPS-calculated dose and dose measured by MOSFET for rectum was within ± 5% in 31 patients, ± 5–10% in 8 patients, and ± 10–15% in 7 patients. CONCLUSION: TPS calculated doses were slightly higher than that measured by MOSFET. The use of small size MOSFET dosimeter is an efficient method for accurately measuring doses in high-dose gradient fields typically seen in brachytherapy. Therefore, to reduce the risk of large errors in dose delivery, in vivo dosimetry can be done in addition to TPS computations. Shiraz University of Medical Sciences 2020-04-01 /pmc/articles/PMC7166216/ /pubmed/32337180 http://dx.doi.org/10.31661/jbpe.v0i0.1065 Text en Copyright: © Journal of Biomedical Physics and Engineering http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 Unported License, ( http://creativecommons.org/licenses/by-nc/4.0/ ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
N., Singh
S., Ahamed
A., Sinha
S., Srivastava
N. K., Painuly
A., Mandal
S. N., Prasad
Rectal and Bladder Dose Measurements in the Intracavitary Applications of Cervical Cancer Treatment with HDR Afterloading System: Comparison of TPS Data with MOSFET Detector
title Rectal and Bladder Dose Measurements in the Intracavitary Applications of Cervical Cancer Treatment with HDR Afterloading System: Comparison of TPS Data with MOSFET Detector
title_full Rectal and Bladder Dose Measurements in the Intracavitary Applications of Cervical Cancer Treatment with HDR Afterloading System: Comparison of TPS Data with MOSFET Detector
title_fullStr Rectal and Bladder Dose Measurements in the Intracavitary Applications of Cervical Cancer Treatment with HDR Afterloading System: Comparison of TPS Data with MOSFET Detector
title_full_unstemmed Rectal and Bladder Dose Measurements in the Intracavitary Applications of Cervical Cancer Treatment with HDR Afterloading System: Comparison of TPS Data with MOSFET Detector
title_short Rectal and Bladder Dose Measurements in the Intracavitary Applications of Cervical Cancer Treatment with HDR Afterloading System: Comparison of TPS Data with MOSFET Detector
title_sort rectal and bladder dose measurements in the intracavitary applications of cervical cancer treatment with hdr afterloading system: comparison of tps data with mosfet detector
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166216/
https://www.ncbi.nlm.nih.gov/pubmed/32337180
http://dx.doi.org/10.31661/jbpe.v0i0.1065
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