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Ivacaftor decreases monocyte sensitivity to interferon-γ in people with cystic fibrosis

This study demonstrates that initiation of the CFTR modulator ivacaftor in people with cystic fibrosis and susceptible CFTR mutations causes an acute reduction in blood monocyte sensitivity to the key proinflammatory cytokine IFN-γ http://bit.ly/2TeI6LG

Detalles Bibliográficos
Autores principales:	Hisert, Katherine B., Birkland, Timothy P., Schoenfelt, Kelly Q., Long, Matthew E., Grogan, Brenda, Carter, Suzanne, Liles, W. Conrad, McKone, Edward F., Becker, Lev, Manicone, Anne M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Respiratory Society 2020
Materias:	Original Research Letters
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167213/ https://www.ncbi.nlm.nih.gov/pubmed/32337217 http://dx.doi.org/10.1183/23120541.00318-2019

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