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The preclinical pharmacological study on HX0969W, a novel water-soluble pro-drug of propofol, in rats

BACKGROUND: Propofol is the most widely used intravenous sedative-hypnotic anesthetic in clinical practice. However, many serious side effects have been related to its lipid emulsion formulation. The pro-drug design approach was used to develop the water-soluble propofol, which could effectively res...

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Detalles Bibliográficos
Autores principales: Zhang, YuJun, Jiang, YingYing, Wang, HaiYan, Wang, Bin, Yang, Jun, Kang, Yi, Chen, Jun, Liu, Jin, Zhang, Wen-sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167245/
https://www.ncbi.nlm.nih.gov/pubmed/32337104
http://dx.doi.org/10.7717/peerj.8922

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