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The preclinical pharmacological study on HX0969W, a novel water-soluble pro-drug of propofol, in rats
BACKGROUND: Propofol is the most widely used intravenous sedative-hypnotic anesthetic in clinical practice. However, many serious side effects have been related to its lipid emulsion formulation. The pro-drug design approach was used to develop the water-soluble propofol, which could effectively res...
Autores principales: | Zhang, YuJun, Jiang, YingYing, Wang, HaiYan, Wang, Bin, Yang, Jun, Kang, Yi, Chen, Jun, Liu, Jin, Zhang, Wen-sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167245/ https://www.ncbi.nlm.nih.gov/pubmed/32337104 http://dx.doi.org/10.7717/peerj.8922 |
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