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Targeting Bacterial Cell Division: A Binding Site-Centered Approach to the Most Promising Inhibitors of the Essential Protein FtsZ
Binary fission is the most common mode of bacterial cell division and is mediated by a multiprotein complex denominated the divisome. The constriction of the Z-ring splits the mother bacterial cell into two daughter cells of the same size. The Z-ring is formed by the polymerization of FtsZ, a bacter...
Autores principales: | Casiraghi, Andrea, Suigo, Lorenzo, Valoti, Ermanno, Straniero, Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167804/ https://www.ncbi.nlm.nih.gov/pubmed/32046082 http://dx.doi.org/10.3390/antibiotics9020069 |
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