Genomic Characterization of New Variant of Hydrogen Sulfide (H(2)S)-Producing Escherichia coli with Multidrug Resistance Properties Carrying the mcr-1 Gene in China †

Colistin is considered to be a ‘last-resort’ antimicrobial for the treatment of multidrug-resistant Gram-negative bacterial infections. Identification of Enterobacteriaceae, carrying the transferable colistin resistance gene mcr-1, has recently provoked a global health concern. This report presents...

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Detalles Bibliográficos
Autores principales: Biswas, Silpak, Elbediwi, Mohammed, Gu, Guimin, Yue, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167817/
https://www.ncbi.nlm.nih.gov/pubmed/32069849
http://dx.doi.org/10.3390/antibiotics9020080
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author Biswas, Silpak
Elbediwi, Mohammed
Gu, Guimin
Yue, Min
author_facet Biswas, Silpak
Elbediwi, Mohammed
Gu, Guimin
Yue, Min
author_sort Biswas, Silpak
collection PubMed
description Colistin is considered to be a ‘last-resort’ antimicrobial for the treatment of multidrug-resistant Gram-negative bacterial infections. Identification of Enterobacteriaceae, carrying the transferable colistin resistance gene mcr-1, has recently provoked a global health concern. This report presents the first detection of a hydrogen sulfide (H(2)S)-producing Escherichia coli variant isolated from a human in China, with multidrug resistance (MDR) properties, including colistin resistance by the mcr-1 gene, which could have great implications for the treatment of human infections.
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spelling pubmed-71678172020-04-21 Genomic Characterization of New Variant of Hydrogen Sulfide (H(2)S)-Producing Escherichia coli with Multidrug Resistance Properties Carrying the mcr-1 Gene in China † Biswas, Silpak Elbediwi, Mohammed Gu, Guimin Yue, Min Antibiotics (Basel) Case Report Colistin is considered to be a ‘last-resort’ antimicrobial for the treatment of multidrug-resistant Gram-negative bacterial infections. Identification of Enterobacteriaceae, carrying the transferable colistin resistance gene mcr-1, has recently provoked a global health concern. This report presents the first detection of a hydrogen sulfide (H(2)S)-producing Escherichia coli variant isolated from a human in China, with multidrug resistance (MDR) properties, including colistin resistance by the mcr-1 gene, which could have great implications for the treatment of human infections. MDPI 2020-02-13 /pmc/articles/PMC7167817/ /pubmed/32069849 http://dx.doi.org/10.3390/antibiotics9020080 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Biswas, Silpak
Elbediwi, Mohammed
Gu, Guimin
Yue, Min
Genomic Characterization of New Variant of Hydrogen Sulfide (H(2)S)-Producing Escherichia coli with Multidrug Resistance Properties Carrying the mcr-1 Gene in China †
title Genomic Characterization of New Variant of Hydrogen Sulfide (H(2)S)-Producing Escherichia coli with Multidrug Resistance Properties Carrying the mcr-1 Gene in China †
title_full Genomic Characterization of New Variant of Hydrogen Sulfide (H(2)S)-Producing Escherichia coli with Multidrug Resistance Properties Carrying the mcr-1 Gene in China †
title_fullStr Genomic Characterization of New Variant of Hydrogen Sulfide (H(2)S)-Producing Escherichia coli with Multidrug Resistance Properties Carrying the mcr-1 Gene in China †
title_full_unstemmed Genomic Characterization of New Variant of Hydrogen Sulfide (H(2)S)-Producing Escherichia coli with Multidrug Resistance Properties Carrying the mcr-1 Gene in China †
title_short Genomic Characterization of New Variant of Hydrogen Sulfide (H(2)S)-Producing Escherichia coli with Multidrug Resistance Properties Carrying the mcr-1 Gene in China †
title_sort genomic characterization of new variant of hydrogen sulfide (h(2)s)-producing escherichia coli with multidrug resistance properties carrying the mcr-1 gene in china †
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167817/
https://www.ncbi.nlm.nih.gov/pubmed/32069849
http://dx.doi.org/10.3390/antibiotics9020080
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