Cargando…

High Prevalence of Strongyloidiasis in Spain: A Hospital-Based Study

Introduction: Strongyloidiasis is a prevailing helminth infection ubiquitous in tropical and subtropical areas, however, seroprevalence data are scarce in migrant populations, particularly for those coming for Asia. Methods: This study aims at evaluating the prevalence of S. stercoralis at the hospi...

Descripción completa

Detalles Bibliográficos
Autores principales: Requena-Méndez, Ana, Salas-Coronas, Joaquin, Salvador, Fernando, Gomez-Junyent, Joan, Villar-Garcia, Judith, Santin, Miguel, Muñoz, Carme, González-Cordón, Ana, Cabezas Fernández, Maria Teresa, Sulleiro, Elena, Arenas, Maria del Mar, Somoza, Dolors, Vazquez-Villegas, Jose, Treviño, Begoña, Rodríguez, Esperanza, Valls, Maria Eugenia, Llaberia-Marcual, Jaume, Subirá, Carme, Muñoz, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167856/
https://www.ncbi.nlm.nih.gov/pubmed/32053864
http://dx.doi.org/10.3390/pathogens9020107
_version_ 1783523603371786240
author Requena-Méndez, Ana
Salas-Coronas, Joaquin
Salvador, Fernando
Gomez-Junyent, Joan
Villar-Garcia, Judith
Santin, Miguel
Muñoz, Carme
González-Cordón, Ana
Cabezas Fernández, Maria Teresa
Sulleiro, Elena
Arenas, Maria del Mar
Somoza, Dolors
Vazquez-Villegas, Jose
Treviño, Begoña
Rodríguez, Esperanza
Valls, Maria Eugenia
Llaberia-Marcual, Jaume
Subirá, Carme
Muñoz, Jose
author_facet Requena-Méndez, Ana
Salas-Coronas, Joaquin
Salvador, Fernando
Gomez-Junyent, Joan
Villar-Garcia, Judith
Santin, Miguel
Muñoz, Carme
González-Cordón, Ana
Cabezas Fernández, Maria Teresa
Sulleiro, Elena
Arenas, Maria del Mar
Somoza, Dolors
Vazquez-Villegas, Jose
Treviño, Begoña
Rodríguez, Esperanza
Valls, Maria Eugenia
Llaberia-Marcual, Jaume
Subirá, Carme
Muñoz, Jose
author_sort Requena-Méndez, Ana
collection PubMed
description Introduction: Strongyloidiasis is a prevailing helminth infection ubiquitous in tropical and subtropical areas, however, seroprevalence data are scarce in migrant populations, particularly for those coming for Asia. Methods: This study aims at evaluating the prevalence of S. stercoralis at the hospital level in migrant populations or long term travellers being attended in out-patient and in-patient units as part of a systematic screening implemented in six Spanish hospitals. A cross-sectional study was conducted and systematic screening for S. stercoralis infection using serological tests was offered to all eligible participants. Results: The overall seroprevalence of S. stercoralis was 9.04% (95%CI 7.76–10.31). The seroprevalence of people with a risk of infection acquired in Africa and Latin America was 9.35% (95%CI 7.01–11.69), 9.22% (7.5–10.93), respectively. The number of individuals coming from Asian countries was significantly smaller and the overall prevalence in these countries was 2.9% (95%CI −0.3–6.2). The seroprevalence in units attending potentially immunosuppressed patients was significantly lower (5.64%) compared with other units of the hospital (10.20%) or Tropical diseases units (13.33%) (p < 0.001). Conclusions: We report a hospital-based strongyloidiasis seroprevalence of almost 10% in a mobile population coming from endemic areas suggesting the need of implementing strongyloidiasis screening in hospitalized patients coming from endemic areas, particularly if they are at risk of immunosuppression.
format Online
Article
Text
id pubmed-7167856
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-71678562020-04-21 High Prevalence of Strongyloidiasis in Spain: A Hospital-Based Study Requena-Méndez, Ana Salas-Coronas, Joaquin Salvador, Fernando Gomez-Junyent, Joan Villar-Garcia, Judith Santin, Miguel Muñoz, Carme González-Cordón, Ana Cabezas Fernández, Maria Teresa Sulleiro, Elena Arenas, Maria del Mar Somoza, Dolors Vazquez-Villegas, Jose Treviño, Begoña Rodríguez, Esperanza Valls, Maria Eugenia Llaberia-Marcual, Jaume Subirá, Carme Muñoz, Jose Pathogens Article Introduction: Strongyloidiasis is a prevailing helminth infection ubiquitous in tropical and subtropical areas, however, seroprevalence data are scarce in migrant populations, particularly for those coming for Asia. Methods: This study aims at evaluating the prevalence of S. stercoralis at the hospital level in migrant populations or long term travellers being attended in out-patient and in-patient units as part of a systematic screening implemented in six Spanish hospitals. A cross-sectional study was conducted and systematic screening for S. stercoralis infection using serological tests was offered to all eligible participants. Results: The overall seroprevalence of S. stercoralis was 9.04% (95%CI 7.76–10.31). The seroprevalence of people with a risk of infection acquired in Africa and Latin America was 9.35% (95%CI 7.01–11.69), 9.22% (7.5–10.93), respectively. The number of individuals coming from Asian countries was significantly smaller and the overall prevalence in these countries was 2.9% (95%CI −0.3–6.2). The seroprevalence in units attending potentially immunosuppressed patients was significantly lower (5.64%) compared with other units of the hospital (10.20%) or Tropical diseases units (13.33%) (p < 0.001). Conclusions: We report a hospital-based strongyloidiasis seroprevalence of almost 10% in a mobile population coming from endemic areas suggesting the need of implementing strongyloidiasis screening in hospitalized patients coming from endemic areas, particularly if they are at risk of immunosuppression. MDPI 2020-02-11 /pmc/articles/PMC7167856/ /pubmed/32053864 http://dx.doi.org/10.3390/pathogens9020107 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Requena-Méndez, Ana
Salas-Coronas, Joaquin
Salvador, Fernando
Gomez-Junyent, Joan
Villar-Garcia, Judith
Santin, Miguel
Muñoz, Carme
González-Cordón, Ana
Cabezas Fernández, Maria Teresa
Sulleiro, Elena
Arenas, Maria del Mar
Somoza, Dolors
Vazquez-Villegas, Jose
Treviño, Begoña
Rodríguez, Esperanza
Valls, Maria Eugenia
Llaberia-Marcual, Jaume
Subirá, Carme
Muñoz, Jose
High Prevalence of Strongyloidiasis in Spain: A Hospital-Based Study
title High Prevalence of Strongyloidiasis in Spain: A Hospital-Based Study
title_full High Prevalence of Strongyloidiasis in Spain: A Hospital-Based Study
title_fullStr High Prevalence of Strongyloidiasis in Spain: A Hospital-Based Study
title_full_unstemmed High Prevalence of Strongyloidiasis in Spain: A Hospital-Based Study
title_short High Prevalence of Strongyloidiasis in Spain: A Hospital-Based Study
title_sort high prevalence of strongyloidiasis in spain: a hospital-based study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167856/
https://www.ncbi.nlm.nih.gov/pubmed/32053864
http://dx.doi.org/10.3390/pathogens9020107
work_keys_str_mv AT requenamendezana highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT salascoronasjoaquin highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT salvadorfernando highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT gomezjunyentjoan highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT villargarciajudith highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT santinmiguel highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT munozcarme highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT gonzalezcordonana highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT cabezasfernandezmariateresa highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT sulleiroelena highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT arenasmariadelmar highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT somozadolors highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT vazquezvillegasjose highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT trevinobegona highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT rodriguezesperanza highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT vallsmariaeugenia highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT llaberiamarcualjaume highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT subiracarme highprevalenceofstrongyloidiasisinspainahospitalbasedstudy
AT munozjose highprevalenceofstrongyloidiasisinspainahospitalbasedstudy