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Machine Learning and Multidrug-Resistant Gram-Negative Bacteria: An Interesting Combination for Current and Future Research

The dissemination of multidrug-resistant Gram-negative bacteria (MDR-GNB) is associated with increased morbidity and mortality in several countries. Machine learning (ML) is a branch of artificial intelligence that consists of conferring on computers the ability to learn from data. In this narrative...

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Detalles Bibliográficos
Autores principales: Giacobbe, Daniele Roberto, Mora, Sara, Giacomini, Mauro, Bassetti, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167992/
https://www.ncbi.nlm.nih.gov/pubmed/32023986
http://dx.doi.org/10.3390/antibiotics9020054
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author Giacobbe, Daniele Roberto
Mora, Sara
Giacomini, Mauro
Bassetti, Matteo
author_facet Giacobbe, Daniele Roberto
Mora, Sara
Giacomini, Mauro
Bassetti, Matteo
author_sort Giacobbe, Daniele Roberto
collection PubMed
description The dissemination of multidrug-resistant Gram-negative bacteria (MDR-GNB) is associated with increased morbidity and mortality in several countries. Machine learning (ML) is a branch of artificial intelligence that consists of conferring on computers the ability to learn from data. In this narrative review, we discuss three existing examples of the application of ML algorithms for assessing three different types of risk: (i) the risk of developing a MDR-GNB infection, (ii) the risk of MDR-GNB etiology in patients with an already clinically evident infection, and (iii) the risk of anticipating the emergence of MDR in GNB through the misuse of antibiotics. In the next few years, we expect to witness an increasingly large number of research studies perfecting the application of ML techniques in the field of MDR-GNB infections. Very importantly, this cannot be separated from the availability of a continuously refined and updated ethical framework allowing an appropriate use of the large datasets of medical data needed to build efficient ML-based support systems that could be shared through appropriate standard infrastructures.
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spelling pubmed-71679922020-04-21 Machine Learning and Multidrug-Resistant Gram-Negative Bacteria: An Interesting Combination for Current and Future Research Giacobbe, Daniele Roberto Mora, Sara Giacomini, Mauro Bassetti, Matteo Antibiotics (Basel) Review The dissemination of multidrug-resistant Gram-negative bacteria (MDR-GNB) is associated with increased morbidity and mortality in several countries. Machine learning (ML) is a branch of artificial intelligence that consists of conferring on computers the ability to learn from data. In this narrative review, we discuss three existing examples of the application of ML algorithms for assessing three different types of risk: (i) the risk of developing a MDR-GNB infection, (ii) the risk of MDR-GNB etiology in patients with an already clinically evident infection, and (iii) the risk of anticipating the emergence of MDR in GNB through the misuse of antibiotics. In the next few years, we expect to witness an increasingly large number of research studies perfecting the application of ML techniques in the field of MDR-GNB infections. Very importantly, this cannot be separated from the availability of a continuously refined and updated ethical framework allowing an appropriate use of the large datasets of medical data needed to build efficient ML-based support systems that could be shared through appropriate standard infrastructures. MDPI 2020-01-31 /pmc/articles/PMC7167992/ /pubmed/32023986 http://dx.doi.org/10.3390/antibiotics9020054 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Giacobbe, Daniele Roberto
Mora, Sara
Giacomini, Mauro
Bassetti, Matteo
Machine Learning and Multidrug-Resistant Gram-Negative Bacteria: An Interesting Combination for Current and Future Research
title Machine Learning and Multidrug-Resistant Gram-Negative Bacteria: An Interesting Combination for Current and Future Research
title_full Machine Learning and Multidrug-Resistant Gram-Negative Bacteria: An Interesting Combination for Current and Future Research
title_fullStr Machine Learning and Multidrug-Resistant Gram-Negative Bacteria: An Interesting Combination for Current and Future Research
title_full_unstemmed Machine Learning and Multidrug-Resistant Gram-Negative Bacteria: An Interesting Combination for Current and Future Research
title_short Machine Learning and Multidrug-Resistant Gram-Negative Bacteria: An Interesting Combination for Current and Future Research
title_sort machine learning and multidrug-resistant gram-negative bacteria: an interesting combination for current and future research
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7167992/
https://www.ncbi.nlm.nih.gov/pubmed/32023986
http://dx.doi.org/10.3390/antibiotics9020054
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