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Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma
Anaplastic (undifferentiated) thyroid carcinoma (ATC) is a rare malignancy which may arise from transformation of a pre-existing differentiated carcinoma. We report the unique case where a lesion of thyroid origin presented with the histological features of mature plasma cells. Immunohistochemistry...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168172/ https://www.ncbi.nlm.nih.gov/pubmed/31936233 http://dx.doi.org/10.3390/diagnostics10010029 |
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author | Mo, Joshua H. Tan, Donald Zhao, Xiaohui S. Tjoa, Tjoson Wang, Beverly Y. |
author_facet | Mo, Joshua H. Tan, Donald Zhao, Xiaohui S. Tjoa, Tjoson Wang, Beverly Y. |
author_sort | Mo, Joshua H. |
collection | PubMed |
description | Anaplastic (undifferentiated) thyroid carcinoma (ATC) is a rare malignancy which may arise from transformation of a pre-existing differentiated carcinoma. We report the unique case where a lesion of thyroid origin presented with the histological features of mature plasma cells. Immunohistochemistry confirmed the lesion to be an anaplastic thyroid carcinoma arising from papillary thyroid carcinoma. A tumor mimicking a malignancy of a different cellular origin can lead clinicians to incorrect treatment approaches. Careful correlation with clinical details and knowledge of these unique presentations is important for reaching the correct diagnosis. |
format | Online Article Text |
id | pubmed-7168172 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71681722020-04-21 Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma Mo, Joshua H. Tan, Donald Zhao, Xiaohui S. Tjoa, Tjoson Wang, Beverly Y. Diagnostics (Basel) Case Report Anaplastic (undifferentiated) thyroid carcinoma (ATC) is a rare malignancy which may arise from transformation of a pre-existing differentiated carcinoma. We report the unique case where a lesion of thyroid origin presented with the histological features of mature plasma cells. Immunohistochemistry confirmed the lesion to be an anaplastic thyroid carcinoma arising from papillary thyroid carcinoma. A tumor mimicking a malignancy of a different cellular origin can lead clinicians to incorrect treatment approaches. Careful correlation with clinical details and knowledge of these unique presentations is important for reaching the correct diagnosis. MDPI 2020-01-08 /pmc/articles/PMC7168172/ /pubmed/31936233 http://dx.doi.org/10.3390/diagnostics10010029 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Mo, Joshua H. Tan, Donald Zhao, Xiaohui S. Tjoa, Tjoson Wang, Beverly Y. Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma |
title | Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma |
title_full | Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma |
title_fullStr | Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma |
title_full_unstemmed | Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma |
title_short | Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma |
title_sort | anaplastic thyroid carcinoma histologically mimicking a plasmacytoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168172/ https://www.ncbi.nlm.nih.gov/pubmed/31936233 http://dx.doi.org/10.3390/diagnostics10010029 |
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