Combining DNA Damage Induction with BCL-2 Inhibition to Enhance Merkel Cell Carcinoma Cytotoxicity

Merkel cell carcinoma (MCC) is a highly lethal skin cancer. MCC tumors rapidly develop resistance to the chemotherapies tested to date. While PD-1/PD-L1 immune checkpoint blockade has demonstrated success in MCC treatment, a significant portion of MCC patients are nonresponsive. Therefore, the press...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Krump, Nathan A., Herlyn, Meenhard, You, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168258/
https://www.ncbi.nlm.nih.gov/pubmed/32093022
http://dx.doi.org/10.3390/biology9020035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168258/
https://www.ncbi.nlm.nih.gov/pubmed/32093022
http://dx.doi.org/10.3390/biology9020035

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