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Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?

Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase...

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Autores principales: Koulenti, Despoina, Arvaniti, Kostoula, Judd, Mathew, Lalos, Natasha, Tjoeng, Iona, Xu, Elena, Armaganidis, Apostolos, Lipman, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168312/
https://www.ncbi.nlm.nih.gov/pubmed/32023886
http://dx.doi.org/10.3390/antibiotics9020051
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author Koulenti, Despoina
Arvaniti, Kostoula
Judd, Mathew
Lalos, Natasha
Tjoeng, Iona
Xu, Elena
Armaganidis, Apostolos
Lipman, Jeffrey
author_facet Koulenti, Despoina
Arvaniti, Kostoula
Judd, Mathew
Lalos, Natasha
Tjoeng, Iona
Xu, Elena
Armaganidis, Apostolos
Lipman, Jeffrey
author_sort Koulenti, Despoina
collection PubMed
description Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase in healthcare costs. Uncertainties remain, however, regarding the cost/benefit balance of VAT treatment. The aim of this narrative review is to discuss the two fundamental and inter-related dilemmas regarding VAT, i.e., (i) how to diagnose VAT? and (ii) should we treat VAT? If yes, should we treat all cases or only selected ones? How should we treat in terms of antibiotic choice, route, treatment duration?
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spelling pubmed-71683122020-04-22 Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? Koulenti, Despoina Arvaniti, Kostoula Judd, Mathew Lalos, Natasha Tjoeng, Iona Xu, Elena Armaganidis, Apostolos Lipman, Jeffrey Antibiotics (Basel) Review Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase in healthcare costs. Uncertainties remain, however, regarding the cost/benefit balance of VAT treatment. The aim of this narrative review is to discuss the two fundamental and inter-related dilemmas regarding VAT, i.e., (i) how to diagnose VAT? and (ii) should we treat VAT? If yes, should we treat all cases or only selected ones? How should we treat in terms of antibiotic choice, route, treatment duration? MDPI 2020-01-31 /pmc/articles/PMC7168312/ /pubmed/32023886 http://dx.doi.org/10.3390/antibiotics9020051 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Koulenti, Despoina
Arvaniti, Kostoula
Judd, Mathew
Lalos, Natasha
Tjoeng, Iona
Xu, Elena
Armaganidis, Apostolos
Lipman, Jeffrey
Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?
title Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?
title_full Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?
title_fullStr Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?
title_full_unstemmed Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?
title_short Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?
title_sort ventilator-associated tracheobronchitis: to treat or not to treat?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168312/
https://www.ncbi.nlm.nih.gov/pubmed/32023886
http://dx.doi.org/10.3390/antibiotics9020051
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