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Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat?
Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168312/ https://www.ncbi.nlm.nih.gov/pubmed/32023886 http://dx.doi.org/10.3390/antibiotics9020051 |
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author | Koulenti, Despoina Arvaniti, Kostoula Judd, Mathew Lalos, Natasha Tjoeng, Iona Xu, Elena Armaganidis, Apostolos Lipman, Jeffrey |
author_facet | Koulenti, Despoina Arvaniti, Kostoula Judd, Mathew Lalos, Natasha Tjoeng, Iona Xu, Elena Armaganidis, Apostolos Lipman, Jeffrey |
author_sort | Koulenti, Despoina |
collection | PubMed |
description | Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase in healthcare costs. Uncertainties remain, however, regarding the cost/benefit balance of VAT treatment. The aim of this narrative review is to discuss the two fundamental and inter-related dilemmas regarding VAT, i.e., (i) how to diagnose VAT? and (ii) should we treat VAT? If yes, should we treat all cases or only selected ones? How should we treat in terms of antibiotic choice, route, treatment duration? |
format | Online Article Text |
id | pubmed-7168312 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71683122020-04-22 Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? Koulenti, Despoina Arvaniti, Kostoula Judd, Mathew Lalos, Natasha Tjoeng, Iona Xu, Elena Armaganidis, Apostolos Lipman, Jeffrey Antibiotics (Basel) Review Ventilator-associated tracheobronchitis (VAT) is an infection commonly affecting mechanically ventilated intubated patients. Several studies suggest that VAT is associated with increased duration of mechanical ventilation (MV) and length of intensive care unit (ICU) stay, and a presumptive increase in healthcare costs. Uncertainties remain, however, regarding the cost/benefit balance of VAT treatment. The aim of this narrative review is to discuss the two fundamental and inter-related dilemmas regarding VAT, i.e., (i) how to diagnose VAT? and (ii) should we treat VAT? If yes, should we treat all cases or only selected ones? How should we treat in terms of antibiotic choice, route, treatment duration? MDPI 2020-01-31 /pmc/articles/PMC7168312/ /pubmed/32023886 http://dx.doi.org/10.3390/antibiotics9020051 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Koulenti, Despoina Arvaniti, Kostoula Judd, Mathew Lalos, Natasha Tjoeng, Iona Xu, Elena Armaganidis, Apostolos Lipman, Jeffrey Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
title | Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
title_full | Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
title_fullStr | Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
title_full_unstemmed | Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
title_short | Ventilator-Associated Tracheobronchitis: To Treat or Not to Treat? |
title_sort | ventilator-associated tracheobronchitis: to treat or not to treat? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168312/ https://www.ncbi.nlm.nih.gov/pubmed/32023886 http://dx.doi.org/10.3390/antibiotics9020051 |
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