Cargando…
The Evaluation of Antibiotic Consumption at the Inpatient Level in Kazakhstan from 2011 to 2018
Antimicrobial agents have a rather special position due to their importance as essential medicines for the treatment of infectious diseases. Evidence-based prescriptions are needed to optimize the use of antimicrobials in humans, as well as to decrease antimicrobial resistance. The aim of this study...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168313/ https://www.ncbi.nlm.nih.gov/pubmed/32024295 http://dx.doi.org/10.3390/antibiotics9020057 |
_version_ | 1783523659806146560 |
---|---|
author | Zhussupova, Gulzira Skvirskaya, Galina Reshetnikov, Vladimir Dragojevic-Simic, Viktorija Rancic, Nemanja Utepova, Dinara Jakovljevic, Mihajlo |
author_facet | Zhussupova, Gulzira Skvirskaya, Galina Reshetnikov, Vladimir Dragojevic-Simic, Viktorija Rancic, Nemanja Utepova, Dinara Jakovljevic, Mihajlo |
author_sort | Zhussupova, Gulzira |
collection | PubMed |
description | Antimicrobial agents have a rather special position due to their importance as essential medicines for the treatment of infectious diseases. Evidence-based prescriptions are needed to optimize the use of antimicrobials in humans, as well as to decrease antimicrobial resistance. The aim of this study was to assess the inpatient consumption of antimicrobial drugs for systemic use in the period 2011–2018 in Kazakhstan. This article presents the results of an evaluation of the inpatient use of antibacterial drugs for systemic use (group J01) for the period 2011–2018 using the anatomical therapeutic chemical (ATC) classification)/defined daily dose (DDD) methodology recommended by the World Health Organization. Inpatient antimicrobial utilization is expressed as DDDs/1000 inhabitants/day (DID). The results of the assessment for inpatient antibiotic use (over an eight-year period) showed a decrease in the total consumption of antibiotics for systemic action in Kazakhstan (2011: 12.72 DID; 2018: 2.74 DID). Among oral formulations, levofloxacin was consumed the most, and cefazolin was consumed the most among the parenteral formulations of antimicrobials. The three drugs consumed the most included cefazolin (first-generation cephalosporin), ceftriaxone (third-generation cephalosporin), and cefuroxime (second-generation cephalosporin). The total consumption of antibacterials for systemic action in Kazakhstan decreased during the analyzed period, but there was an irrational use of certain groups of drugs. |
format | Online Article Text |
id | pubmed-7168313 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71683132020-04-22 The Evaluation of Antibiotic Consumption at the Inpatient Level in Kazakhstan from 2011 to 2018 Zhussupova, Gulzira Skvirskaya, Galina Reshetnikov, Vladimir Dragojevic-Simic, Viktorija Rancic, Nemanja Utepova, Dinara Jakovljevic, Mihajlo Antibiotics (Basel) Article Antimicrobial agents have a rather special position due to their importance as essential medicines for the treatment of infectious diseases. Evidence-based prescriptions are needed to optimize the use of antimicrobials in humans, as well as to decrease antimicrobial resistance. The aim of this study was to assess the inpatient consumption of antimicrobial drugs for systemic use in the period 2011–2018 in Kazakhstan. This article presents the results of an evaluation of the inpatient use of antibacterial drugs for systemic use (group J01) for the period 2011–2018 using the anatomical therapeutic chemical (ATC) classification)/defined daily dose (DDD) methodology recommended by the World Health Organization. Inpatient antimicrobial utilization is expressed as DDDs/1000 inhabitants/day (DID). The results of the assessment for inpatient antibiotic use (over an eight-year period) showed a decrease in the total consumption of antibiotics for systemic action in Kazakhstan (2011: 12.72 DID; 2018: 2.74 DID). Among oral formulations, levofloxacin was consumed the most, and cefazolin was consumed the most among the parenteral formulations of antimicrobials. The three drugs consumed the most included cefazolin (first-generation cephalosporin), ceftriaxone (third-generation cephalosporin), and cefuroxime (second-generation cephalosporin). The total consumption of antibacterials for systemic action in Kazakhstan decreased during the analyzed period, but there was an irrational use of certain groups of drugs. MDPI 2020-02-02 /pmc/articles/PMC7168313/ /pubmed/32024295 http://dx.doi.org/10.3390/antibiotics9020057 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhussupova, Gulzira Skvirskaya, Galina Reshetnikov, Vladimir Dragojevic-Simic, Viktorija Rancic, Nemanja Utepova, Dinara Jakovljevic, Mihajlo The Evaluation of Antibiotic Consumption at the Inpatient Level in Kazakhstan from 2011 to 2018 |
title | The Evaluation of Antibiotic Consumption at the Inpatient Level in Kazakhstan from 2011 to 2018 |
title_full | The Evaluation of Antibiotic Consumption at the Inpatient Level in Kazakhstan from 2011 to 2018 |
title_fullStr | The Evaluation of Antibiotic Consumption at the Inpatient Level in Kazakhstan from 2011 to 2018 |
title_full_unstemmed | The Evaluation of Antibiotic Consumption at the Inpatient Level in Kazakhstan from 2011 to 2018 |
title_short | The Evaluation of Antibiotic Consumption at the Inpatient Level in Kazakhstan from 2011 to 2018 |
title_sort | evaluation of antibiotic consumption at the inpatient level in kazakhstan from 2011 to 2018 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168313/ https://www.ncbi.nlm.nih.gov/pubmed/32024295 http://dx.doi.org/10.3390/antibiotics9020057 |
work_keys_str_mv | AT zhussupovagulzira theevaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT skvirskayagalina theevaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT reshetnikovvladimir theevaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT dragojevicsimicviktorija theevaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT rancicnemanja theevaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT utepovadinara theevaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT jakovljevicmihajlo theevaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT zhussupovagulzira evaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT skvirskayagalina evaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT reshetnikovvladimir evaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT dragojevicsimicviktorija evaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT rancicnemanja evaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT utepovadinara evaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 AT jakovljevicmihajlo evaluationofantibioticconsumptionattheinpatientlevelinkazakhstanfrom2011to2018 |