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Alginate-encapsulated brain-derived neurotrophic factor–overexpressing mesenchymal stem cells are a promising drug delivery system for protection of auditory neurons

The cochlear implant outcome is possibly improved by brain-derived neurotrophic factor treatment protecting spiral ganglion neurons. Implantation of genetically modified mesenchymal stem cells may enable the required long-term brain-derived neurotrophic factor administration. Encapsulation of mesenc...

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Detalles Bibliográficos
Autores principales: Schwieger, Jana, Hamm, Anika, Gepp, Michael M., Schulz, André, Hoffmann, Andrea, Lenarz, Thomas, Scheper, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168777/
https://www.ncbi.nlm.nih.gov/pubmed/32341778
http://dx.doi.org/10.1177/2041731420911313