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Busulfan systemic exposure and its relationship with efficacy and safety in hematopoietic stem cell transplantation in children: a meta-analysis

BACKGROUND: Busulfan (Bu) is a key component of several conditioning regimens used before hematopoietic stem cell transplantation (HSCT). However, the optimum systemic exposure (expressed as the area under the concentration-time curve [AUC]) of Bu for clinical outcome in children is controversial. M...

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Detalles Bibliográficos
Autores principales:	Feng, Xinying, Wu, Yunjiao, Zhang, Jingru, Li, Jiapeng, Zhu, Guanghua, Fan, Duanfang, Yang, Changqing, Zhao, Libo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168843/ https://www.ncbi.nlm.nih.gov/pubmed/32312247 http://dx.doi.org/10.1186/s12887-020-02028-6

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