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Cross-sectional analysis of circulating tumor DNA in primary colorectal cancer at surgery and during post-surgery follow-up by liquid biopsy

BACKGROUND: Liquid biopsy (LB) in early-stage, non-metastatic colorectal cancer (CRC) must be sensitive enough to detect extremely low circulating tumor DNA (ctDNA) levels. This challenge has been seldom and non-systematically investigated. METHODS: Next generation sequencing (NGS) and digital PCR (...

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Detalles Bibliográficos
Autores principales: Allegretti, Matteo, Cottone, Giuliano, Carboni, Fabio, Cotroneo, Ettore, Casini, Beatrice, Giordani, Elena, Amoreo, Carla Azzurra, Buglioni, Simonetta, Diodoro, Maria, Pescarmona, Edoardo, Zazza, Settimio, Federici, Orietta, Zeuli, Massimo, Conti, Laura, Cigliana, Giovanni, Fiorentino, Francesco, Valle, Mario, Giacomini, Patrizio, Spinella, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168847/
https://www.ncbi.nlm.nih.gov/pubmed/32312295
http://dx.doi.org/10.1186/s13046-020-01569-z

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