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Cross-sectional analysis of circulating tumor DNA in primary colorectal cancer at surgery and during post-surgery follow-up by liquid biopsy
BACKGROUND: Liquid biopsy (LB) in early-stage, non-metastatic colorectal cancer (CRC) must be sensitive enough to detect extremely low circulating tumor DNA (ctDNA) levels. This challenge has been seldom and non-systematically investigated. METHODS: Next generation sequencing (NGS) and digital PCR (...
Autores principales: | Allegretti, Matteo, Cottone, Giuliano, Carboni, Fabio, Cotroneo, Ettore, Casini, Beatrice, Giordani, Elena, Amoreo, Carla Azzurra, Buglioni, Simonetta, Diodoro, Maria, Pescarmona, Edoardo, Zazza, Settimio, Federici, Orietta, Zeuli, Massimo, Conti, Laura, Cigliana, Giovanni, Fiorentino, Francesco, Valle, Mario, Giacomini, Patrizio, Spinella, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168847/ https://www.ncbi.nlm.nih.gov/pubmed/32312295 http://dx.doi.org/10.1186/s13046-020-01569-z |
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