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Transcriptome analysis and functional characterization of cerebral organoids in bipolar disorder

BACKGROUND: Reprogramming human induced pluripotent stem cells (iPSCs) from somatic cells and generating three-dimensional brain organoids from these iPSCs provide access to live human neuronal tissue with disease-specific genetic backgrounds. METHODS: Cerebral organoids were generated from iPSCs of...

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Detalles Bibliográficos
Autores principales:	Kathuria, Annie, Lopez-Lengowski, Kara, Vater, Magdalena, McPhie, Donna, Cohen, Bruce M., Karmacharya, Rakesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168850/ https://www.ncbi.nlm.nih.gov/pubmed/32306996 http://dx.doi.org/10.1186/s13073-020-00733-6

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