ATLANTIS: a randomised multi-arm phase II biomarker-directed umbrella screening trial of maintenance targeted therapy after chemotherapy in patients with advanced or metastatic urothelial cancer

BACKGROUND: Metastatic urothelial cancer (UC) is the eighth most common cause of cancer death in the UK. Standard first-line treatment, for most patients, is cytotoxic chemotherapy. Although UC is initially sensitive to chemotherapy, relapse is almost inevitable and outcomes are poor; median overall...

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Detalles Bibliográficos
Autores principales: Fulton, Ben, Jones, Robert, Powles, Thomas, Crabb, Simon, Paul, James, Birtle, Alison, Chowdhury, Simon, Hussain, Syed, Morris, Anna, Soulis, Eileen, Morrison, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168999/
https://www.ncbi.nlm.nih.gov/pubmed/32306987
http://dx.doi.org/10.1186/s13063-020-04283-5

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