Neurokinin-1 Receptor Signaling Is Required for Efficient Ca(2+) Flux in T-Cell-Receptor-Activated T Cells

Efficient Ca(2+) flux induced during cognate T cell activation requires signaling the T cell receptor (TCR) and unidentified G-protein-coupled receptors (GPCRs). T cells express the neurokinin-1 receptor (NK1R), a GPCR that mediates Ca(2+) flux in excitable and non-excitable cells. However, the role...

Descripción completa

Detalles Bibliográficos
Autores principales: Morelli, Adrian E., Sumpter, Tina L., Rojas-Canales, Darling M., Bandyopadhyay, Mohna, Chen, Zhizhao, Tkacheva, Olga, Shufesky, William J., Wallace, Callen T., Watkins, Simon C., Berger, Alexandra, Paige, Christopher J., Falo, Louis D., Larregina, Adriana T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169378/
https://www.ncbi.nlm.nih.gov/pubmed/32160549
http://dx.doi.org/10.1016/j.celrep.2020.02.054

Ejemplares similares

Ejemplares similares