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Human Metapneumovirus: A Largely Unrecognized Threat to Human Health
Human metapneumovirus (HMPV) infects most children by five years of age. The virus can cause both upper and lower respiratory tract disease and can be life threatening. High-risk populations include young children who are exposed to virus for the first time and the elderly. Currently, there is no st...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169409/ https://www.ncbi.nlm.nih.gov/pubmed/32069879 http://dx.doi.org/10.3390/pathogens9020109 |
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author | Russell, Charles J. Penkert, Rhiannon R. Kim, Sonnie Hurwitz, Julia L. |
author_facet | Russell, Charles J. Penkert, Rhiannon R. Kim, Sonnie Hurwitz, Julia L. |
author_sort | Russell, Charles J. |
collection | PubMed |
description | Human metapneumovirus (HMPV) infects most children by five years of age. The virus can cause both upper and lower respiratory tract disease and can be life threatening. High-risk populations include young children who are exposed to virus for the first time and the elderly. Currently, there is no standard treatment nor licensed vaccine for HMPV, although several attractive vaccine candidates have been developed for pre-clinical studies. A raised awareness of the impact of HMPV on public health is needed to drive research, complete vaccine development, and thereby prevent significant virus-associated morbidities and mortalities worldwide. |
format | Online Article Text |
id | pubmed-7169409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-71694092020-04-20 Human Metapneumovirus: A Largely Unrecognized Threat to Human Health Russell, Charles J. Penkert, Rhiannon R. Kim, Sonnie Hurwitz, Julia L. Pathogens Opinion Human metapneumovirus (HMPV) infects most children by five years of age. The virus can cause both upper and lower respiratory tract disease and can be life threatening. High-risk populations include young children who are exposed to virus for the first time and the elderly. Currently, there is no standard treatment nor licensed vaccine for HMPV, although several attractive vaccine candidates have been developed for pre-clinical studies. A raised awareness of the impact of HMPV on public health is needed to drive research, complete vaccine development, and thereby prevent significant virus-associated morbidities and mortalities worldwide. MDPI 2020-02-13 /pmc/articles/PMC7169409/ /pubmed/32069879 http://dx.doi.org/10.3390/pathogens9020109 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Opinion Russell, Charles J. Penkert, Rhiannon R. Kim, Sonnie Hurwitz, Julia L. Human Metapneumovirus: A Largely Unrecognized Threat to Human Health |
title | Human Metapneumovirus: A Largely Unrecognized Threat to Human Health |
title_full | Human Metapneumovirus: A Largely Unrecognized Threat to Human Health |
title_fullStr | Human Metapneumovirus: A Largely Unrecognized Threat to Human Health |
title_full_unstemmed | Human Metapneumovirus: A Largely Unrecognized Threat to Human Health |
title_short | Human Metapneumovirus: A Largely Unrecognized Threat to Human Health |
title_sort | human metapneumovirus: a largely unrecognized threat to human health |
topic | Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169409/ https://www.ncbi.nlm.nih.gov/pubmed/32069879 http://dx.doi.org/10.3390/pathogens9020109 |
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