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Human Metapneumovirus: A Largely Unrecognized Threat to Human Health

Human metapneumovirus (HMPV) infects most children by five years of age. The virus can cause both upper and lower respiratory tract disease and can be life threatening. High-risk populations include young children who are exposed to virus for the first time and the elderly. Currently, there is no st...

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Autores principales: Russell, Charles J., Penkert, Rhiannon R., Kim, Sonnie, Hurwitz, Julia L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169409/
https://www.ncbi.nlm.nih.gov/pubmed/32069879
http://dx.doi.org/10.3390/pathogens9020109
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author Russell, Charles J.
Penkert, Rhiannon R.
Kim, Sonnie
Hurwitz, Julia L.
author_facet Russell, Charles J.
Penkert, Rhiannon R.
Kim, Sonnie
Hurwitz, Julia L.
author_sort Russell, Charles J.
collection PubMed
description Human metapneumovirus (HMPV) infects most children by five years of age. The virus can cause both upper and lower respiratory tract disease and can be life threatening. High-risk populations include young children who are exposed to virus for the first time and the elderly. Currently, there is no standard treatment nor licensed vaccine for HMPV, although several attractive vaccine candidates have been developed for pre-clinical studies. A raised awareness of the impact of HMPV on public health is needed to drive research, complete vaccine development, and thereby prevent significant virus-associated morbidities and mortalities worldwide.
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spelling pubmed-71694092020-04-20 Human Metapneumovirus: A Largely Unrecognized Threat to Human Health Russell, Charles J. Penkert, Rhiannon R. Kim, Sonnie Hurwitz, Julia L. Pathogens Opinion Human metapneumovirus (HMPV) infects most children by five years of age. The virus can cause both upper and lower respiratory tract disease and can be life threatening. High-risk populations include young children who are exposed to virus for the first time and the elderly. Currently, there is no standard treatment nor licensed vaccine for HMPV, although several attractive vaccine candidates have been developed for pre-clinical studies. A raised awareness of the impact of HMPV on public health is needed to drive research, complete vaccine development, and thereby prevent significant virus-associated morbidities and mortalities worldwide. MDPI 2020-02-13 /pmc/articles/PMC7169409/ /pubmed/32069879 http://dx.doi.org/10.3390/pathogens9020109 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Opinion
Russell, Charles J.
Penkert, Rhiannon R.
Kim, Sonnie
Hurwitz, Julia L.
Human Metapneumovirus: A Largely Unrecognized Threat to Human Health
title Human Metapneumovirus: A Largely Unrecognized Threat to Human Health
title_full Human Metapneumovirus: A Largely Unrecognized Threat to Human Health
title_fullStr Human Metapneumovirus: A Largely Unrecognized Threat to Human Health
title_full_unstemmed Human Metapneumovirus: A Largely Unrecognized Threat to Human Health
title_short Human Metapneumovirus: A Largely Unrecognized Threat to Human Health
title_sort human metapneumovirus: a largely unrecognized threat to human health
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169409/
https://www.ncbi.nlm.nih.gov/pubmed/32069879
http://dx.doi.org/10.3390/pathogens9020109
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