Troxerutin Prevents 5-Fluorouracil Induced Morphological Changes in the Intestinal Mucosa: Role of Cyclooxygenase-2 Pathway

Intestinal mucositis is a common complication associated with 5-fluorouracil (5-FU), a chemotherapeutic agent used for cancer treatment. Troxerutin (TRX), a semi-synthetic flavonoid extracted from Dimorphandra gardneriana, has been reported as a potent antioxidant and anti-inflammatory agent. In the...

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Detalles Bibliográficos
Autores principales: de Miranda, João Antônio Leal, Martins, Conceição da Silva, Fideles, Lázaro de Sousa, Barbosa, Maria Lucianny Lima, Barreto, João Erivan Façanha, Pimenta, Helder Bindá, Freitas, Francisco Orlando Rafael, Pimentel, Paulo Vitor de Souza, Teixeira, Claudio Silva, Scafuri, Ariel Gustavo, dos Santos Luciano, Maria Claudia, Araújo, Joabe Lima, Rocha, Jefferson Almeida, Vieira, Icaro Gusmão Pinto, Ricardo, Nágila Maria Pontes Silva, da Silva Campelo, Matheus, Ribeiro, Maria Elenir Nobre Pinho, de Castro Brito, Gerly Anne, Cerqueira, Gilberto Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169416/
https://www.ncbi.nlm.nih.gov/pubmed/31936203
http://dx.doi.org/10.3390/ph13010010

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