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Deep and Densely Connected Networks for Classification of Diabetic Retinopathy

Diabetes has recently emerged as a worldwide problem, and diabetic retinopathy is an abnormal state associated with the human retina. Due to the increase in daily screen-related activities of modern human beings, diabetic retinopathy is more prevalent among adults, leading to minor and major blindne...

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Autores principales: Riaz, Hamza, Park, Jisu, Choi, Hojong, Kim, Hyunchul, Kim, Jungsuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169456/
https://www.ncbi.nlm.nih.gov/pubmed/31906601
http://dx.doi.org/10.3390/diagnostics10010024
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author Riaz, Hamza
Park, Jisu
Choi, Hojong
Kim, Hyunchul
Kim, Jungsuk
author_facet Riaz, Hamza
Park, Jisu
Choi, Hojong
Kim, Hyunchul
Kim, Jungsuk
author_sort Riaz, Hamza
collection PubMed
description Diabetes has recently emerged as a worldwide problem, and diabetic retinopathy is an abnormal state associated with the human retina. Due to the increase in daily screen-related activities of modern human beings, diabetic retinopathy is more prevalent among adults, leading to minor and major blindness. Doctors and clinicians are unable to perform early diagnoses due to the large number of patients. To solve this problem, this study introduces a classification model for retinal images that distinguishes between the various stages of diabetic retinopathy. This work involves deploying deep and densely connected networks for retinal image analysis with training from scratch. Dense connections between the convolutional layers of the network are an essential factor to enhance accuracy owing to the deeper supervision between layers. Another factor is the growth rate that further assists our model in learning more sophisticated feature maps regarding retinal images from every stage of the network. We compute the area under the curve, sensitivity, and specificity, particularly for messidor-2 and EyePACS. Compared to existing approaches, our method achieved better results, with an approximate rise rate of 0.01, 0.03, and 0.01, respectively. Therefore, computer-aided programs can help in diagnostic centers as automated detection systems.
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spelling pubmed-71694562020-04-22 Deep and Densely Connected Networks for Classification of Diabetic Retinopathy Riaz, Hamza Park, Jisu Choi, Hojong Kim, Hyunchul Kim, Jungsuk Diagnostics (Basel) Article Diabetes has recently emerged as a worldwide problem, and diabetic retinopathy is an abnormal state associated with the human retina. Due to the increase in daily screen-related activities of modern human beings, diabetic retinopathy is more prevalent among adults, leading to minor and major blindness. Doctors and clinicians are unable to perform early diagnoses due to the large number of patients. To solve this problem, this study introduces a classification model for retinal images that distinguishes between the various stages of diabetic retinopathy. This work involves deploying deep and densely connected networks for retinal image analysis with training from scratch. Dense connections between the convolutional layers of the network are an essential factor to enhance accuracy owing to the deeper supervision between layers. Another factor is the growth rate that further assists our model in learning more sophisticated feature maps regarding retinal images from every stage of the network. We compute the area under the curve, sensitivity, and specificity, particularly for messidor-2 and EyePACS. Compared to existing approaches, our method achieved better results, with an approximate rise rate of 0.01, 0.03, and 0.01, respectively. Therefore, computer-aided programs can help in diagnostic centers as automated detection systems. MDPI 2020-01-02 /pmc/articles/PMC7169456/ /pubmed/31906601 http://dx.doi.org/10.3390/diagnostics10010024 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Riaz, Hamza
Park, Jisu
Choi, Hojong
Kim, Hyunchul
Kim, Jungsuk
Deep and Densely Connected Networks for Classification of Diabetic Retinopathy
title Deep and Densely Connected Networks for Classification of Diabetic Retinopathy
title_full Deep and Densely Connected Networks for Classification of Diabetic Retinopathy
title_fullStr Deep and Densely Connected Networks for Classification of Diabetic Retinopathy
title_full_unstemmed Deep and Densely Connected Networks for Classification of Diabetic Retinopathy
title_short Deep and Densely Connected Networks for Classification of Diabetic Retinopathy
title_sort deep and densely connected networks for classification of diabetic retinopathy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169456/
https://www.ncbi.nlm.nih.gov/pubmed/31906601
http://dx.doi.org/10.3390/diagnostics10010024
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